Evidence map›Paper›PMID 36897975›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

Endoplasmic reticulum-bound ANAC013 factor is cleaved by RHOMBOID-LIKE 2 during the initial response to hypoxia in

Emese Eysholdt-Derzsó, Tilo Renziehausen, Stephanie Frings, Stephanie Frohn, Kira von Bongartz, Clara P Igisch, Justina Mann, Lisa Häger, Julia Macholl, David Leisse and 10 more

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
17.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. A synthetic ERFVII-dependent circuit in yeast sheds light on the regulation of early hypoxic responses of plants.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  5. Regulation of mixotrophy inMicrobiology (Reading, England) · 2026
    Article
  6. Article
  7. Review
  8. Advances in seed hypoxia research.Plant physiology · 2024
    Article
  9. Review
  10. Review
  11. Perception and processing of stress signals by plant mitochondria.The Plant journal : for cell and molecular biology · 2024
    Review
  12. Article
  13. Genome-Wide Identification of NAC Gene Family Members of Tree Peony (International journal of molecular sciences · 2024
    Article
  14. Establishment and Maintenance of Heat-Stress Memory in Plants.International journal of molecular sciences · 2024
    Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 5 institutions in 2 countries.

Emese Eysholdt-DerzsóPlant Developmental Biology and Plant Physiology, University of Kiel, 24118 Kiel, Germany.
Tilo RenziehausenInstitute of Biology I, Rheinisch-Westfälische Technische Hochschule Aachen University, 52074 Aachen, Germany.
Stephanie FringsInstitute of Biology I, Rheinisch-Westfälische Technische Hochschule Aachen University, 52074 Aachen, Germany.
Stephanie FrohnInstitute of Biology I, Rheinisch-Westfälische Technische Hochschule Aachen University, 52074 Aachen, Germany.
Kira von BongartzInstitute of Biology I, Rheinisch-Westfälische Technische Hochschule Aachen University, 52074 Aachen, Germany.
Clara P IgischInstitute of Biology I, Rheinisch-Westfälische Technische Hochschule Aachen University, 52074 Aachen, Germany.
Justina MannInstitute of Biology I, Rheinisch-Westfälische Technische Hochschule Aachen University, 52074 Aachen, Germany.
Lisa HägerInstitute of Biology I, Rheinisch-Westfälische Technische Hochschule Aachen University, 52074 Aachen, Germany.
Julia MachollPlant Biotechnology, Faculty of Biology, University of Bielefeld, 33615 Bielefeld, Germany.
David LeissePlant Biotechnology, Faculty of Biology, University of Bielefeld, 33615 Bielefeld, Germany.
Niels HoffmannInstitute of Biology I, Rheinisch-Westfälische Technische Hochschule Aachen University, 52074 Aachen, Germany.
Katharina WinkelsInstitute of Biology I, Rheinisch-Westfälische Technische Hochschule Aachen University, 52074 Aachen, Germany.
Pia WannerInstitute of Biology I, Rheinisch-Westfälische Technische Hochschule Aachen University, 52074 Aachen, Germany.
Jonas De BackerDepartment of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, Belgium.ORCID 0000-0001-9473-6614
Xiaopeng LuoDepartment of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, Belgium.
Margret SauterPlant Developmental Biology and Plant Physiology, University of Kiel, 24118 Kiel, Germany.ORCID 0000-0002-7370-643X
Inge De ClercqDepartment of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, Belgium.
Joost T van DongenInstitute of Biology I, Rheinisch-Westfälische Technische Hochschule Aachen University, 52074 Aachen, Germany.ORCID 0000-0001-7944-9289
Jos H M SchippersDepartment of Molecular Genetics, Seed Development, Leibniz Institute of Plant Genetics and Crop Plant Research (IPK) Gatersleben, 06466 Seeland, Germany.ORCID 0000-0001-7934-126X
Romy R Schmidt-SchippersInstitute of Biology I, Rheinisch-Westfälische Technische Hochschule Aachen University, 52074 Aachen, Germany.ORCID 0000-0002-3395-0673
RWTH Aachen University · DEBielefeld University · DEVlaams Instituut voor Biotechnologie · BEChristian-Albrechts-Universität zu Kiel · DELeibniz-Institut für Pflanzengenetik und Kulturpflanzenforschung (IPK) · DE

Funding

European Research Council 949808
6 · The paper itself

Abstract

Aerobic reactions are essential to sustain plant growth and development. Impaired oxygen availability due to excessive water availability, e.g., during waterlogging or flooding, reduces plant productivity and survival. Consequently, plants monitor oxygen availability to adjust growth and metabolism accordingly. Despite the identification of central components in hypoxia adaptation in recent years, molecular pathways involved in the very early activation of low-oxygen responses are insufficiently understood. Here, we characterized three endoplasmic reticulum (ER)-anchored

Indexed as

ArabidopsisArabidopsis ProteinsSerine EndopeptidasesTranscription FactorsEndoplasmic ReticulumFibrinogenGene Expression Regulation, PlantHumansHypoxiaOxygenANAC013 protein, ArabidopsisANAC017 protein, ArabidopsisArabidopsis ProteinsFibrinogenOxygenRBL2 protein, ArabidopsisSerine EndopeptidasesTranscription FactorsANAChypoxiaproteolytic cleavagerhomboid proteasetranscription factor

Identifiers

PMID36897975
PMCPMC10242721
OpenAlexW4323825330

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.