Evidence map›Paper›PMID 36897543›Full record

ArticleTranslational stroke research2024

Cerebral Hemodynamics Underlying Artery-to-Artery Embolism in Symptomatic Intracranial Atherosclerotic Disease.

Xueyan Feng, Hui Fang, Bonaventure Y M Ip, Ka Lung Chan, Shuang Li, Xuan Tian, Lina Zheng, Yuying Liu, Linfang Lan, Haipeng Liu and 10 more

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Translational stroke research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 6 institutions in 3 countries.

Xueyan FengDepartment of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.ORCID 0000-0001-5019-8893
Hui FangDepartment of Neurology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Bonaventure Y M IpDepartment of Medicine & Therapeutics, the Chinese University of Hong Kong, Hong Kong SAR, China.
Ka Lung ChanDepartment of Neurology, the First Affiliated Hospital of Jinan University, Guangzhou, China.
Shuang LiDepartment of Medicine & Therapeutics, the Chinese University of Hong Kong, Hong Kong SAR, China.
Xuan TianDepartment of Medicine & Therapeutics, the Chinese University of Hong Kong, Hong Kong SAR, China.
Lina ZhengDepartment of Medicine & Therapeutics, the Chinese University of Hong Kong, Hong Kong SAR, China.
Yuying LiuDepartment of Medicine & Therapeutics, the Chinese University of Hong Kong, Hong Kong SAR, China.
Linfang LanDepartment of Neurology, the First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Haipeng LiuResearch Centre for Intelligent Healthcare, Faculty of Health and Life Sciences, Coventry University, Coventry, UK.
Jill AbrigoDepartment of Imaging and Interventional Radiology, the Chinese University of Hong Kong, Hong Kong SAR, China.
Sze Ho MaDepartment of Medicine & Therapeutics, the Chinese University of Hong Kong, Hong Kong SAR, China.
Florence S Y FanDepartment of Medicine & Therapeutics, the Chinese University of Hong Kong, Hong Kong SAR, China.
Vincent H L IpDepartment of Medicine & Therapeutics, the Chinese University of Hong Kong, Hong Kong SAR, China.
Yannie O Y SooDepartment of Medicine & Therapeutics, the Chinese University of Hong Kong, Hong Kong SAR, China.
Vincent C T MokDepartment of Medicine & Therapeutics, the Chinese University of Hong Kong, Hong Kong SAR, China.
Bo SongDepartment of Neurology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Thomas W LeungDepartment of Medicine & Therapeutics, the Chinese University of Hong Kong, Hong Kong SAR, China.ORCID 0000-0001-8193-0709
Yuming XuDepartment of Neurology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, China. xuyuming@zzu.edu.cn.
Xinyi LengDepartment of Medicine & Therapeutics, the Chinese University of Hong Kong, Hong Kong SAR, China. xinyi_leng@cuhk.edu.hk.ORCID 0000-0001-7300-6647
Chinese University of Hong Kong · HKFirst Affiliated Hospital of Zhengzhou University · CNFirst Affiliated Hospital of Jinan University · CNIntelligent Health (United Kingdom) · GBSun Yat-sen University · CNZhengzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Artery-to-artery embolism (AAE) is a common stroke mechanism in intracranial atherosclerotic disease (ICAD), associated with a considerable risk of recurrent stroke. We aimed to investigate cerebral hemodynamic features associated with AAE in symptomatic ICAD. Patients with anterior-circulation, symptomatic ICAD confirmed in CT angiography (CTA) were recruited. We classified probable stroke mechanisms as isolated parent artery atherosclerosis occluding penetrating artery, AAE, hypoperfusion, and mixed mechanisms, largely based on infarct topography. CTA-based computational fluid dynamics (CFD) models were built to simulate blood flow across culprit ICAD lesions. Translesional pressure ratio (PR = Pressure

Indexed as

Cerebrovascular CirculationHemodynamicsIntracranial ArteriosclerosisAgedCerebral AngiographyComputed Tomography AngiographyFemaleHumansIntracranial EmbolismMaleMiddle AgedEmbolismHemodynamicsIntracranial AtherosclerosisPrognosisStroke

Identifiers

PMID36897543
OpenAlexW4323807152

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.