Evidence map›Paper›PMID 36897438›Full record

ArticleJournal, genetic engineering & biotechnology2023

Insight study on synthesis and antibacterial mechanism of silver nanoparticles prepared from indigenous plant source of Jharkhand.

Koel Mukherjee, Namrata Bhagat, Madhubala Kumari, Arnab Roy Choudhury, Biplab Sarkar, Barnali Dasgupta Ghosh

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Article in Journal, genetic engineering & biotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Koel MukherjeeDepartment of Bioengineering and Biotechnology, Birla Institute of Technology, Mesra, Jharkhand, 835215, Ranchi, India. koelmukherjee@bitmesra.ac.in.ORCID http://orcid.org/0000-0001-9897-5217
Namrata BhagatDepartment of Bioengineering and Biotechnology, Birla Institute of Technology, Mesra, Jharkhand, 835215, Ranchi, India.
Madhubala KumariDepartment of Bioengineering and Biotechnology, Birla Institute of Technology, Mesra, Jharkhand, 835215, Ranchi, India.
Arnab Roy ChoudhuryDownstream Agro-Processing Division, ICAR-National Institute of Secondary Agriculture, Namkum, Jharkhand, 834010, Ranchi, India.
Biplab SarkarIndian Council of Agricultural Research-Indian Institute of Agricultural Biotechnology, Garhkhatanga, Jharkhand, 834010, Ranchi, India. biplab_puru@yahoo.co.in.
Barnali Dasgupta GhoshDepartment of Chemistry, Birla Institute of Technology, Mesra, Ranchi, Jharkhand, 835215, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Ag-NPs by green synthesis has a notable interest because of their eco-friendliness, economic views, feasibility, and applications in a wide range. Herein, native plants of Jharkhand (Polygonum plebeium, Litsea glutinosa, and Vangueria spinosus) were selected for the current work of Ag-NP synthesis and further antibacterial activity. Green synthesis was performed for Ag-NPs using Silver nitrate solution as precursor and the dried leaf extract performs as a reductant and stabilizer here.

resultVisually Ag-NP formation was observed along with a colour change and confirmed by UV-visible spectrophotometry on which an absorbance peak occurs at around 400-450nm. Further characterization was done on DLS, FTIR, FESEM, and XRD. Size around 45-86 nm of synthesized Ag-NPs was predicted through DLS. The synthesized Ag-NPs exhibited significant antibacterial activity against Bacillus subtilis (Gram-positive bacteria) and Salmonella typhi (Gram-negative bacteria). The finest antibacterial activity was disclosed by the Ag-NPs synthesized by Polygonum plebeium extract. The diameter of the zone of inhibition in the bacterial plate measured was 0-1.8 mm in Bacillus and 0-2.2 mm in Salmonella typhi. Protein-Protein interaction study was performed to study the effect of Ag-NPs towards different antioxidant enzyme system of bacterial cell.

conclusionPresent work suggest the Ag-NPs synthesized from P. plebeium were more stable for long term and might have prolonged antibacterial activity. In the future, these Ag-NPs can be applied in various fields like antimicrobial research, wound healing, drug delivery, bio-sensing, tumour/cancer cell treatment, and detector (detect solar energy). Schematic representation of Ag-NPs green synthesis, characterization, antibacterial activity and at the end, in silico study to analyse the mechanism of antibacterial activity.

Indexed as

Ag-NPsIndigenous plantLitsea glutinosaPolygonum plebeiumVangueria spinosus

Identifiers

PMID36897438
PMCPMC10006383

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