Evidence map›Paper›PMID 36897227›Full record

ArticlePediatrics2023

Requests for Directed Blood Donations.

Meaghann S Weaver, Marianne E M Yee, Courtney E Lawrence, Armand H Matheny Antommaria, Ross M Fasano

Abstract read
In one paragraph

Article in Pediatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Meaghann S WeaverDepartment of Pediatrics, University of Nebraska, Omaha, Nebraska.
Marianne E M YeeDepartment of Pathology and Laboratory Medicine, Center for Transfusion and Cellular Therapy.
Courtney E LawrenceDivision of Pediatric Hematology, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Armand H Matheny AntommariaEthics Center, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Ross M FasanoDepartment of Pathology and Laboratory Medicine, Center for Transfusion and Cellular Therapy.

Funding

Kinetics of Red Blood Cell Clearance in Chronically Transfused Children with Sickle Cell DiseaseK23HL146904 · NHLBI · EMORY UNIVERSITY · PI YEE, MARIANNE ELAINE MCPHERSON · 2020 to 2024
$853k
NHLBI NIH HHS K23 HL146904
6 · The paper itself

Abstract

This Ethics Rounds presents a request for directed blood donation. Two parents feel helpless in the setting of their daughter's new leukemia diagnosis and want to directly help their child by providing their own blood for a transfusion. They express hesitancy about trusting the safety of a stranger's blood. Commentators assess this case in the setting of blood as a scarce community resource during a national blood shortage. Commentators review the child's best interest, future risks, and harm-benefit considerations. Commentators recognize the professional integrity, humility, and courage of the physician to admit his own lack of knowledge on the subject and to seek help rather than claim directed donation is not possible without further investigation into options. Shared ideals such as altruism, trust, equity, volunteerism, and solidarity are recognized as values relevant to sustainment of a community blood supply. Pediatric hematologists, a blood bank director, transfusion medicine specialists, and an ethicist conclude that directed donation is only justified by lower risks to the recipient in particular circumstances.

Indexed as

Blood DonationParentsBlood TransfusionChildDirected Tissue DonationHumans

Identifiers

PMID36897227
PMCPMC10998552

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.