ArticleOrganic letters2023
Rapid Generation of P(V)-F Bonds Through the Use of Sulfone Iminium Fluoride Reagents.
Article in Organic letters, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- A Bench-Stable Fluorophosphine Nickel(0) Complex and Its Catalytic Application.Angewandte Chemie (International ed. in English) · 2025Article
- Diversity Oriented Clicking for Modular Synthesis.Nature reviews. Methods primers · 2025Article
- Late-stage (radio)fluorination of alkyl phosphonates via electrophilic activation.Nature communications · 2024Article
- Chloroimidazolium Deoxyfluorination Reagent with HThe Journal of organic chemistry · 2024Article
- Article
- A modified Beckmann rearrangement for the facile synthesis of amidines and imidatesRSC advances · 2023Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Phosphorus-fluorine bonds have become increasingly relevant in the pharmaceutical industry. To continue their exploration, more efficient synthetic methods are needed. Here, we report the application of sulfone iminium fluoride (SIF) reagents to the synthesis of P(V)-F bonds. The SIF reagents promote the deoxyfluorination of phosphinic acids in just 60 s with excellent yields and scope. The same P(V)-F products can also be synthesized from secondary phosphine oxides using an SIF reagent.
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Registered trials
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