Evidence map›Paper›PMID 36897214›Full record

ArticleBlood advances2023

Targeting the deacetylase SIRT6 unveils spliceosome deregulation as exploitable vulnerability for aggressive myeloma.

Elisa Gelli, Debora Soncini, Pamela Becherini, Claudia Martinuzzi, Katia Todoerti, Antonia Cagnetta, Sara Aquino, Fabio Guolo, Maurizio Miglino, Santina Bruzzone and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Blood advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Elisa GelliClinic of Hematology, Department of Internal Medicine, University of Genoa, Genoa, Italy.
Debora SonciniClinic of Hematology, Department of Internal Medicine, University of Genoa, Genoa, Italy.
Pamela BecheriniClinic of Hematology, Department of Internal Medicine, University of Genoa, Genoa, Italy.
Claudia MartinuzziIRCCS Ospedale Policlinico San Martino, Genoa, Italy.
Katia TodoertiDepartment of Hematology, Fondazione Cà Granda IRCCS Policlinico, Milan, Italy.
Antonia CagnettaClinic of Hematology, Department of Internal Medicine, University of Genoa, Genoa, Italy.ORCID 0000-0003-1973-3768
Sara AquinoDivision of Hematology and Hematopoietic Stem Cell Transplantation Unit, Ospedale Policlinico San Martino, Genoa, Italy.
Fabio GuoloClinic of Hematology, Department of Internal Medicine, University of Genoa, Genoa, Italy.
Maurizio MiglinoClinic of Hematology, Department of Internal Medicine, University of Genoa, Genoa, Italy.
Santina BruzzoneDepartment of Experimental Medicine, University of Genova, Genova, Italy.
Alessio NencioniDepartment of Internal Medicine, University of Genoa, Genoa, Italy.
Antonino NeriScientific Directorate, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy.
Roberto M LemoliClinic of Hematology, Department of Internal Medicine, University of Genoa, Genoa, Italy.
Michele CeaClinic of Hematology, Department of Internal Medicine, University of Genoa, Genoa, Italy.ORCID 0000-0002-1530-6729

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Multiple MyelomaSirtuinsHumansSpliceosomesSIRT6 protein, humanSirtuins

Identifiers

PMID36897214
PMCPMC10362259

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.