ReviewAmyotrophic lateral sclerosis & frontotemporal degeneration2023
Clinical testing panels for ALS: global distribution, consistency, and challenges.
Abstract readReview
In one paragraph
Review in Amyotrophic lateral sclerosis & frontotemporal degeneration, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Mutations in the tail and rod domains of the neurofilament heavy-chain gene increase the risk of ALS.Annals of clinical and translational neurology · 2024Pooled it
- Large-scale exome analyses reveal new rare variant contributions in amyotrophic lateral sclerosis.Nature genetics · 2026Article
- Amyotrophic Lateral Sclerosis (ALS) Genetics and Microbiota: A Comprehensive Review.International journal of molecular sciences · 2026Review
- Update and recommendations on genetic testing for amyotrophic lateral sclerosis in clinical practice: a Brazilian expert view.Frontiers in neurology · 2026Review
- Entering the era of precision medicine to treat amyotrophic lateral sclerosis.Molecular neurodegeneration · 2025Review
- Nutritional Interventions in Amyotrophic Lateral Sclerosis: From Ketogenic Diet and Neuroprotective Nutrients to the Microbiota-Gut-Brain Axis Regulation.Molecular neurobiology · 2025Review
- Clinical genetic testing in Parkinson's disease should become part of routine patient care.Brain : a journal of neurology · 2024Article
- Generating Clinical-Grade Gene-Disease Validity Classifications Through the ClinGen Data Platforms.Annual review of biomedical data science · 2024Review
- Characterizing proteomic and transcriptomic features of missense variants in amyotrophic lateral sclerosis genes.Brain : a journal of neurology · 2023Article
- Evaluating the Utility of REVEL and CADD for Interpreting Variants in Amyotrophic Lateral Sclerosis Genes.Human mutation · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
38 authors.
Allison A DilliottDepartment of Neurology and Neurosurgery, McGill University, Montreal, Canada.ORCID 0000-0003-3863-9304
Ahmad Al NasserSchulich School of Medicine and Dentistry, Western University, London, Canada.
Marwa ElnagheebDepartment of Genetics, University of North Carolina, Chapel Hill, NC, USA.
Jennifer FifitaCentre for MND Research, Macquarie Medical School, Macquarie University, Sydney, Australia.
Lyndal HendenCentre for MND Research, Macquarie Medical School, Macquarie University, Sydney, Australia.
Ingrid M KeselerDepartment of Biomedical Data Science, Stanford University, Stanford, CA, USA.
Steven LenzPreventionGenetics, Marshfield, WI, USA.
Heather MarriottDepartment of Basic and Clinical Neuroscience, King's College London, London, UK.
Emily MccannCentre for MND Research, Macquarie Medical School, Macquarie University, Sydney, Australia.
Maysen MesarosMedical University of South Carolina, Charleston, SC, USA.
Sarah Opie-MartinDepartment of Basic and Clinical Neuroscience, King's College London, London, UK.ORCID 0000-0003-0951-8589
Emma OwensDepartment of Genetics, University of North Carolina, Chapel Hill, NC, USA.
Brooke PalusDepartment of Genetics, University of North Carolina, Chapel Hill, NC, USA.
Justyne RossDepartment of Genetics, University of North Carolina, Chapel Hill, NC, USA.
Zhanjun WangDepartment of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, China.
Hannah WhiteInvitae, San Francisco, CA, USA.
Ammar Al-ChalabiDepartment of Basic and Clinical Neuroscience, King's College London, London, UK.ORCID 0000-0002-4924-7712
Peter M AndersenDepartment of Clinical Sciences, Neurosciences, Umeå University, Umeå, Sweden.
Michael BenatarDepartment of Neurology, University of Miami, Miami, FL, USA.ORCID 0000-0003-4241-5135
Ian BlairCentre for MND Research, Macquarie Medical School, Macquarie University, Sydney, Australia.
Johnathan Cooper-KnockDepartment of Neuroscience, Sheffield Institute for Translational Neuroscience (SITraN), University of Sheffield, Sheffield, UK.
Elizabeth A HarringtonDepartment of Neurology, Columbia University Vagelos College of Physicians and Surgeons, New York City, NY, USA.
Jeannine HeckmannDivision of Neurology, University of Cape Town, Cape Town, South Africa.
John LandersDepartment of Neurology, University of Massachusetts Amherst, Amherst, MA, USA.
Cristiane MorenoDepartment of Neurology, University of Sao Paulo, Sao Paulo, Brazil.
Melissa NelDivision of Neurology, University of Cape Town, Cape Town, South Africa.
Evadnie RampersaudCenter for Applied Bioinformatics, St. Jude's Children's Hospital, Memphis, TN, USA.
Jennifer RoggenbuckDepartment of Internal Medicine, Ohio State University, Columbus, OH, USA.
Guy RouleauDepartment of Neurology and Neurosurgery, McGill University, Montreal, Canada.
Bryan TraynorNeuromuscular Diseases Research Unit, Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA.
Marka Van BlitterswijkDepartment of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.
Wouter Van RheenenDepartment of Neurology, University Medical Center Utrecht Brain Center, Utrecht, The Netherlands, and.
Jan VeldinkDepartment of Neurology, University Medical Center Utrecht Brain Center, Utrecht, The Netherlands, and.
Jochen WeishauptDepartment of Neurology, Heidelberg University, Heidelberg, Germany.
Luke DruryPreventionGenetics, Marshfield, WI, USA.
Matthew B HarmsDepartment of Neurology, Columbia University Vagelos College of Physicians and Surgeons, New York City, NY, USA.
Sali M K FarhanDepartment of Genetics, Montreal Neurological Institute and Hospital, McGill University, Montreal, Canada.ORCID 0000-0001-5936-0957
Amyotrophic lateral sclerosis spectrum disorders Gene Curation Expert Panel
Funding
The Clinical Genome Resource – Advancing genomic medicine through biocuration and expert assessment of genes and variants at scaleU24HG009650 · NHGRI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI JONATHAN S BERG, Jessica Ezzell Hunter · 2021 to 2026
$30.0MGenome wide SNP analysis in Parkinson's diseaseZ01AG000949 · NIA · NATIONAL INSTITUTE ON AGING · PI SINGLETON, ANDREW B · 2006 to 2008
$2.6MIntramural NIH HHS Z01 AG000949NHGRI NIH HHS U24 HG009650
Abstract
PubMed holds no abstract for this paper.
Indexed as
Amyotrophic Lateral SclerosisC9orf72 ProteinGenetic TestingHumansMutationC9orf72 ProteinAmyotrophic lateral sclerosisclinical laboratoriesgene-disease relationshipsgene panelsgenetic testing
Identifiers
What OpenQuestion holds
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Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.