Evidence map›Paper›PMID 36896571›Full record

ArticleEndocrinology, diabetes & metabolism2023

Clinical, cytological and ultrasonographic features of incidental thyroid cancer in a hospital-based study in vietnam.

Bay Quang Nguyen, Hau Thi Tran, Huong Thi Thu Nguyen, Thanh Xuan Nguyen, Thu Thi Hoai Nguyen, Tam Ngoc Nguyen, Huyen Thi Thanh Vu

Open access · goldAbstract read
In one paragraph

Article in Endocrinology, diabetes & metabolism, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Bay Quang NguyenInternal Medicine Department, Hanoi Medical University, Hanoi, Vietnam.ORCID 0000-0003-2847-2256
Hau Thi TranNational Hospital of Endocrinology, Hanoi, Vietnam.ORCID 0000-0001-8273-6174
Huong Thi Thu NguyenDepartment of Geriatrics, Hanoi Medical University, Hanoi, Vietnam.ORCID 0000-0002-6738-7663
Thanh Xuan NguyenDepartment of Geriatrics, Hanoi Medical University, Hanoi, Vietnam.ORCID 0000-0002-9858-9268
Thu Thi Hoai NguyenDepartment of Geriatrics, Hanoi Medical University, Hanoi, Vietnam.ORCID 0000-0002-5024-2812
Tam Ngoc NguyenDepartment of Geriatrics, Hanoi Medical University, Hanoi, Vietnam.ORCID 0000-0001-9265-1887
Huyen Thi Thanh VuDepartment of Geriatrics, Hanoi Medical University, Hanoi, Vietnam.ORCID 0000-0002-3132-3801
Hanoi Medical University · VNVietnam National Children's Hospital · VN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThyroid nodules are common diseases of the endocrine system, with a 5% prevalence rate in the general population. This study aimed to identify prevalence, clinical, cytological and ultrasonographic features of incidental thyroid cancer and its associated factors in Vietnam.

methodsThis cross-sectional descriptive study consisted of 208 patients with incidental thyroid nodules detected by ultrasound at the Endocrinology Department, Bach Mai Hospital, Hanoi, Vietnam between November 2019 and August 2020. Clinical information, sonography characteristics of thyroid nodules, results of fine-needle aspiration biopsy (FNAB), postoperative pathology and lymph node metastasis were collected. A multiple logistic regression model was used to estimate factors associated with thyroid cancer.

resultsA total of 272 thyroid nodules (from 208 participants) were included in this study. The mean age was 47.2 ± 12.0 (years). The rate of incidental thyroid cancer patients detected was 17.3%. Nodules <1 cm in size were significantly more prevalent for malignant nodules. The size of more than half of thyroid cancer nodules was 0.50-0.99 cm. Postoperative pathology of all nodules with Bethesda V and VI was papillary thyroid cancer which was consistent with cytological results. 33.3% of thyroid cancer patients have lymph node metastasis. The regression model showed that thyroid cancer was more likely to occur at a younger age (≤ 45 years vs. >45 years, OR 2.8; 95% CI: 1.3-6.1), taller-than-wide nodules (OR 6.8; 95% CI: 2.3-20.2) and hypo-echoic nodules (OR 5.2; 95% CI: 1.7-15.9).

conclusionThe study showed that the prevalence of incidental thyroid cancers was 17.3%, of which 100% was papillary carcinoma. People under the age of 45 and the presence of ultrasound characteristics, such as taller-than-wide and hypoechoic nodules increased risk for malignancy.

Indexed as

Thyroid NeoplasmsThyroid NoduleAdultCross-Sectional StudiesHospitalsHumansLymphatic MetastasisMiddle AgedVietnamincidentalthyroid cancerthyroid nodules FNAB

Identifiers

PMID36896571
PMCPMC10164435
OpenAlexW4323804940

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.