Evidence map›Paper›PMID 36896456›Full record

ArticleScience and technology of advanced materials2023

pH responsive cationic guar gum-borate self-healing hydrogels for muco-adhesion.

Athira Sreedevi Madhavikutty, Arvind K Singh Chandel, Ching-Cheng Tsai, Natsuko F Inagaki, Seiichi Ohta, Taichi Ito

Open access · goldAbstract read
In one paragraph

Article in Science and technology of advanced materials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Athira Sreedevi MadhavikuttyDepartment of Chemical System Engineering, The University of Tokyo, Tokyo 113-8656, Japan.ORCID https://orcid.org/0000-0003-0128-6365
Arvind K Singh ChandelCenter for Disease Biology and Integrative Medicine, The University of Tokyo, Tokyo 113-0033, Japan.ORCID https://orcid.org/0000-0002-7130-7734
Ching-Cheng TsaiDepartment of Bioengineering, The University of Tokyo, Tokyo 113-8656, Japan.ORCID https://orcid.org/0000-0002-4353-0445
Natsuko F InagakiCenter for Disease Biology and Integrative Medicine, The University of Tokyo, Tokyo 113-0033, Japan.ORCID https://orcid.org/0000-0002-6309-9023
Seiichi OhtaDepartment of Chemical System Engineering, The University of Tokyo, Tokyo 113-8656, Japan.
Taichi ItoDepartment of Chemical System Engineering, The University of Tokyo, Tokyo 113-8656, Japan.ORCID https://orcid.org/0000-0002-1589-8242
The University of Tokyo · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We developed a new muco-adhesive hydrogel composed of cationic guar gum (CGG) and boric acid (BA). The CGG-BA precursor solution of 0.5-2% w/v concentration exhibited fluidity at low pH (3-5), while gelation occurred within 1 min at physiological pH (7-8) conditions. Scanning electron microscopy and Fourier-transform infrared spectroscopy results confirmed the change in physical and chemical behavior, respectively, with change in pH. The pH-responsive self-healing ability was analyzed through microscopy and rheology. CGG-BA hydrogels showed good self-healing property at pH 7.4. The

Indexed as

hydrogelsmuco-adhesionSelf-healing

Identifiers

PMID36896456
PMCPMC9990695
OpenAlexW4319316798

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.