ArticleFrontiers in microbiology2023
A MALDI-TOF MS library for rapid identification of human commensal gut bacteria from the class
Article in Frontiers in microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 18 citations in OpenAlex.
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- The cancer-microbiome axis: Mechanisms and emerging therapeutic strategies.Seminars in immunopathology · 2026Review
- maldipickr dereplicates microbial MALDI-TOF spectra to facilitate multiplexed isolation.Bioinformatics advances · 2026Article
- Antagonistic drug interactions protect commensalGut microbes · 2025Article
- Proton-pump inhibitors increaseGut microbes · 2025Article
- Synergy between culturomics and metagenomics of health status-associated gut bacteria originating from non-IBD and IBD populations.Scientific reports · 2025Article
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- Live Biotherapeutic Products for Metabolic Diseases: Development Strategies, Challenges, and Future Directions.Journal of microbiology and biotechnology · 2025Review
- Metabolic diversity and responses of anteater clostridial isolates to chitin-based substrates.Frontiers in veterinary science · 2025Article
- Exposure of gut bacterial isolates to the anthelminthic drugs, ivermectin and moxidectin, leads to antibiotic-like phenotypes of growth inhibition and adaptation.Communications biology · 2024Article
- Using matrix assisted laser desorption ionisation mass spectrometry combined with machine learning for vaccine authenticity screening.NPJ vaccines · 2024Article
- High-throughput anaerobic screening for identifying compounds acting against gut bacteria in monocultures or communities.Nature protocols · 2024Review
- Spectrometric Characterization of Clinical and Environmental Isolates ofJournal of fungi (Basel, Switzerland) · 2023Article
Corrections and comments
- Erratum issued
Authors and funding
18 authors at 7 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Microbial isolates from culture can be identified using 16S or whole-genome sequencing which generates substantial costs and requires time and expertise. Protein fingerprinting Methods: We constructed a database containing mass spectral profiles (MSP) from 142 bacterial strains representing 47 species and 21 genera within the class Results: For validation, we used 58 sequence-confirmed strains and the CLOSTRI-TOF database successfully identified 98 and 93% of the strains, respectively, in two independent laboratories. Next, we applied the database to 326 isolates from stool of healthy Swiss volunteers and identified 264 (82%) of all isolates (compared to 170 (52.1%) with the Bruker-Daltonics library alone), thus classifying 60% of the formerly unknown isolates. Discussion: We describe a new open-source MSP database for fast and accurate identification of the
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.