Evidence map›Paper›PMID 36896214›Full record

ArticleAdvances in radiation oncology

Radiation Therapy in the German Hodgkin Study Group HD 16 and HD 17 Trials: Quality Assurance and Dosimetric Analysis for Hodgkin Lymphoma in the Modern Era.

Michael Oertel, Dominik Hering, Nina Nacke, Christopher Kittel, Kai Kröger, Jan Kriz, Michael Fuchs, Christian Baues, Dirk Vordermark, Rita Engenhart-Cabillic and 8 more

Open access · goldAbstract read
In one paragraph

Article in Advances in radiation oncology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Article
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  7. Article
  8. [Cardiovascular risk evaluation in the treatment of Hodgkin lymphoma-are we on the road to individualized planning?]Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 9 institutions in 3 countries.

Michael OertelDepartment of Radiation Oncology, University Hospital Muenster, Muenster, Germany.
Dominik HeringDepartment of Radiation Oncology, University Hospital Muenster, Muenster, Germany.
Nina NackeDepartment of Radiation Oncology, University Hospital Muenster, Muenster, Germany.
Christopher KittelDepartment of Radiation Oncology, University Hospital Muenster, Muenster, Germany.
Kai KrögerDepartment of Radiation Oncology, University Hospital Muenster, Muenster, Germany.
Jan KrizDepartment of Radiation Oncology, Alexianer Clemenshospital Muenster, Muenster, Germany.
Michael FuchsDepartment of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne, Düsseldorf, University Hospital of Cologne, Cologne, Germany.
Christian BauesDepartment of Radiation Oncology and Cyberknife Center, University Hospital of Cologne, Cologne, Germany.
Dirk VordermarkDepartment of Radiation Oncology, University Hospital Halle (Saale), Halle (Saale), Germany.
Rita Engenhart-CabillicDepartment of Radiotherapy and Radiation Oncology, University Hospital Giessen-Marburg, Marburg, Germany.
Klaus HerfarthDepartment of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany.
Peter LukasDepartment of Radiooncology, Medical University Innsbruck, Innsbruck, Austria.
Heinz SchmidbergerDepartment of Radiotherapy and Radiation Oncology, University Hospital Mainz, Mainz, Germany.
Simone MarnitzDepartment of Radiation Oncology and Cyberknife Center, University Hospital of Cologne, Cologne, Germany.
Peter BorchmannDepartment of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne, Düsseldorf, University Hospital of Cologne, Cologne, Germany.
Andreas EngertDepartment of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne, Düsseldorf, University Hospital of Cologne, Cologne, Germany.
Uwe HaverkampDepartment of Radiation Oncology, University Hospital Muenster, Muenster, Germany.
Hans Theodor EichDepartment of Radiation Oncology, University Hospital Muenster, Muenster, Germany.
University Hospital Münster · DEDüsseldorf University Hospital · DEUniversity Hospital Cologne · DEClemenshospital Münster · DEHeidelberg University · DEInnsbruck Medical University · ATJohannes Gutenberg University Mainz · DEUniversitätsklinikum Gießen und Marburg · DEUniversity Hospital in Halle · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Radiation therapy (RT) is an integral part of treatment concepts for early-stage Hodgkin lymphoma. This analysis reports on RT quality in the recent HD16 and 17 trials of the German Hodgkin Study Group (GHSG). Methods and Materials: All RT plans of involved-node radiation therapy (INRT) in HD 17 were requested for analysis, along with 100 and 50 involved-field radiation therapy (IFRT) plans in HD 16 and 17, respectively. A structured assessment regarding field design and protocol adherence was performed by the reference radiation oncology panel of the GHSG. Results: Overall, 100 (HD 16) and 176 (HD 17) patients were eligible for analysis. In HD 16, 84% of RT series were evaluated as correct, with significant improvement compared with the predecessor studies ( Conclusions: The latest study generation of the GHSG demonstrates an improved quality in RT. A modern INRT design could be established without deterioration in quality. On a conceptual level, an individual consideration of the appropriate RT technique has to be performed.

Identifiers

PMID36896214
PMCPMC9991533
OpenAlexW4313334750

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.