Evidence map›Paper›PMID 36895954›Full record

ArticleBrain communications2023

Variability in objective sleep is associated with Alzheimer's pathology and cognition.

Laura Fenton, A Lisette Isenberg, Vahan Aslanyan, Daniel Albrecht, Joey A Contreras, Joy Stradford, Teresa Monreal, Judy Pa

Open access · goldAbstract read
In one paragraph

Article in Brain communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
8.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 32 citations in OpenAlex.

  1. Trial
  2. Article
  3. Night-to-night rapid eye movement sleep variability: A relevant marker of early amyloid-β deposition.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Observational
  4. Article
  5. Longitudinal association between sleep and Alzheimer's pathology.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  6. Article
  7. Article
  8. Sleep duration promotes resistance and resilience to tau in older women at risk for Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Brain communications · 2025
    Article
  14. Article
  15. Article
  16. Article
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  19. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Laura FentonAlzheimer Disease Research Center, Department of Neurology, Keck School of Medicine of USC, University of Southern California, Los Angeles, CA 90033, USA.ORCID https://orcid.org/0000-0001-5234-3927
A Lisette IsenbergAlzheimer's Disease Cooperative Study (ADCS), Department of Neurosciences, University of California, San Diego, CA 92037, USA.
Vahan AslanyanDepartment of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA 90032, USA.
Daniel AlbrechtAlzheimer's Disease Cooperative Study (ADCS), Department of Neurosciences, University of California, San Diego, CA 92037, USA.
Joey A ContrerasAlzheimer's Disease Cooperative Study (ADCS), Department of Neurosciences, University of California, San Diego, CA 92037, USA.
Joy StradfordAlzheimer's Disease Cooperative Study (ADCS), Department of Neurosciences, University of California, San Diego, CA 92037, USA.
Teresa MonrealMark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.
Judy PaAlzheimer Disease Research Center, Department of Neurology, Keck School of Medicine of USC, University of Southern California, Los Angeles, CA 90033, USA.
University of California San Diego · USUniversity of Southern California · US

Funding

Effects of physical activity on brain function and network connectivity in MCIR01AG046928 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI TOGA, ARTHUR W · 2015 to 2020
$3.2M
NIA NIH HHS R01 AG046928
6 · The paper itself

Abstract

Both sleep duration and sleep efficiency have been associated with risk of Alzheimer's disease, suggesting that interventions to promote optimal sleep may be a way to reduce Alzheimer's disease risk. However, studies often focus on average sleep measures, usually from self-report questionnaires, ignoring the role of intra-individual variability in sleep across nights quantified from objective sleep measures. The current cross-sectional study sought to investigate the role of intra-individual variability in accelerometer-based objective sleep duration and sleep efficiency in relation to

Indexed as

agingAlzheimer’s diseaseAPOEcognitionsleep

Identifiers

PMID36895954
PMCPMC9989141
OpenAlexW4321012968

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.