Evidence map›Paper›PMID 36895888›Full record

ArticleCritical care explorations2023

Effect of Laryngoscope Blade Size on First Pass Success of Tracheal Intubation in Critically Ill Adults.

Kevin R Landefeld, Seiji Koike, Ran Ran, Matthew W Semler, Christopher Barnes, Susan B Stempek, David R Janz, Todd W Rice, Derek W Russell, Wesley H Self and 4 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Critical care explorations, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06232837 (Macintosh Blade Size During Laryngoscopy for Endotracheal Intubation in Operative Rooms. A Nationwide Prospective Observational Study.), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06232837 completednot on this mapstarted 2024, after this paper: background citation

Macintosh Blade Size During Laryngoscopy for Endotracheal Intubation in Operative Rooms. A Nationwide Prospective Observational Study.

TypeobservationalSponsorUniversity Hospital, Clermont-FerrandRan2024 to 2025Enrolled3,058ConditionsIntubation Complication, Intubation, Difficult or Failed, Endotracheal IntubationArmsDirect laryngoscopy using Macintosh blade
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 1 country.

Kevin R LandefeldDepartment of Medicine, Division of Pulmonary, Allergy, and Critical Care Medicine, Oregon Health and Science University School of Medicine, Portland, OR.
Seiji KoikeBiostatistics and Design Program, Oregon Health and Science University, Portland, OR.
Ran RanDepartment of Medicine, Division of Pulmonary, Allergy, and Critical Care Medicine, Oregon Health and Science University School of Medicine, Portland, OR.
Matthew W SemlerDivision of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University School of Medicine, Nashville, TN.
Christopher BarnesDepartment of Anesthesiology and Pain Medicine, University of Washington, Seattle, WA.
Susan B StempekDepartment of Medicine, Division of Pulmonary & Critical Care Medicine, Lahey Hospital & Medical Center, Burlington, MA.
David R JanzUniversity Medical Center New Orleans, New Orleans, LA.
Todd W RiceDivision of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University School of Medicine, Nashville, TN.
Derek W RussellDepartment of Medicine, Division of Pulmonary, Allergy & Critical Care Medicine, University of Alabama at Birmingham Heersink School of Medicine, Birmingham, AL.
Wesley H SelfVanderbilt Institute for Clinical and Translational Research and Department of Emergency Medicine, Vanderbilt University Medical Center, Nashville, TN.
Derek VonderhaarDepartment of Pulmonary and Critical Care Medicine, Ochsner Health System New Orleans, New Orleans, LA.
Jason R WestDepartment of Emergency Medicine, New York Health + Hospitals | Lincoln, New York, NY.
Jonathan D CaseyDivision of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University School of Medicine, Nashville, TN.
Akram KhanDepartment of Medicine, Division of Pulmonary, Allergy, and Critical Care Medicine, Oregon Health and Science University School of Medicine, Portland, OR.
Vanderbilt University · USOchsner Health System · USOregon Health & Science University · USUniversity Medical Center New Orleans · USUniversity of Washington · USVanderbilt University Medical Center · US

Funding

Bag-Mask Ventilation to PreVent Hypoxemia during Tracheal Intubation in the Emergency Department: A Clinical TrialK23HL153584 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI CASEY, JONATHAN DALE · 2020 to 2024
$900k
Activated Neutrophilic Exosome as Biomarker and Therapeutic Target in COPDK08HL148514 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI RUSSELL, DEREK · 2020 to 2024
$824k
NHLBI NIH HHS K08 HL148514NHLBI NIH HHS K23 HL153584
6 · The paper itself

Abstract

Tracheal intubation (TI) is a common procedure in critical care, often performed with a Macintosh curved blade used for direct laryngoscopy (DL). Minimal evidence informs the choice between Macintosh blade sizes during TI. We hypothesized that Macintosh 4 blade would have higher first-attempt success than Macintosh 3 blade during DL.

designRetrospective analysis using a propensity score and inverse probability weighting of data from six prior multicenter randomized trials. SETTING AND

participantsAdult patients who underwent nonelective TI at participating emergency departments and ICUs. We compared the first-pass success of TI with DL in subjects intubated with a size 4 Macintosh blade on the first TI attempt to subjects with a size 3 Macintosh blade on the first TI attempt. MAIN

resultsAmong 979 subjects, 592 (60.5%) had TI using DL with a Macintosh blade, of whom 362 (37%) were intubated with a size 4 blade and 222 (22.7%) with a size 3 blade. We used inverse probability weighting with a propensity score for analyzing data. We found that patients intubated with a size 4 blade had a worse (higher) Cormack-Lehane grade of glottic view than patients intubated with a size 3 blade (adjusted odds ratio [aOR], 1.458; 95% CI, 1.064-2.003; CONCLUSIONS AND RELEVANCE: In critically ill adults undergoing TI using DL with a Macintosh blade, patients intubated using a size 4 blade on first attempt had a worse glottic view and a lower first pass success than patients intubated with a size 3 Macintosh blade. Further prospective studies are needed to examine the optimal approach to selecting laryngoscope blade size during TI of critically ill adults.

Indexed as

airway managementcritical carelaryngoscopesizelaryngoscopymechanical ventilationtracheal intubation

Identifiers

PMID36895888
PMCPMC9990830
OpenAlexW4323309450

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.