Evidence map›Paper›PMID 36895585›Full record

ReviewMaterials advances2023

Advancements in bacteriophage therapies and delivery for bacterial infection.

Hannah A Durr, Nic D Leipzig

Open access · goldAbstract readReview
In one paragraph

Review in Materials advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 2 pooled it
10.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 43 citations in OpenAlex.

  1. Pooled it
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  6. Inhibition ofACS omega · 2025
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  18. Aerosolic Application of Phages AgainstPHAGE (New Rochelle, N.Y.) · 2024
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Hannah A DurrDepartment of Integrated Biosciences, University of Akron Ohio 44325 USA.
Nic D LeipzigDepartment of Chemical, Biomolecular, and Corrosion Engineering, University of Akron Ohio 44325 USA nl21@uakron.edu.ORCID https://orcid.org/0000-0001-9454-7661
University of Akron · US

Funding

Development of synergistic oxygenating antibacterial hydrogel dressings for reducing infection in diabetic woundsR21AR074743 · NIAMS · UNIVERSITY OF AKRON · PI LEIPZIG, NIC D · 2020 to 2021
$358k
NIAMS NIH HHS R21 AR074743
6 · The paper itself

Abstract

Having co-evolved with bacteria over hundreds of millions of years, bacteriophage are effective killers of specific bacterial hosts. Therefore, phage therapies for infection are a promising treatment avenue, can provide a solution for antibiotic resistant bacterial infections, and have specified targeting of infectious bacteria while allowing the natural microbiome to survive which systemic antibiotics often wipe out. Many phages have well studied genomes that can be modified to change target, widen target range, or change mode of action of killing bacterial hosts. Phage delivery can also be designed to increase efficacy of treatment, including encapsulation and delivery

Identifiers

PMID36895585
PMCPMC9987412
OpenAlexW4318711726

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.