Evidence map›Paper›PMID 36895384›Full record

ArticleHeliyon2023

Compounds originating from the edible mushroom

Orr Shahar, Idan Pereman, Hazem Khamisie, Nirit Ezov, Ofer Danay, Ali Khattib, Ron Schweitzer, Soliman Khatib, Jamal Mahajna

Open access · goldAbstract read
In one paragraph

Article in Heliyon, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Comparative Genomic Analysis of Two Monokaryons ofJournal of fungi (Basel, Switzerland) · 2025
    Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Orr ShaharDepartment of Nutrition and Natural Products, Migal - Galilee Research Institute, Kiryat Shmona, Israel.
Idan PeremanDepartment of Nutrition and Natural Products, Migal - Galilee Research Institute, Kiryat Shmona, Israel.
Hazem KhamisieDepartment of Nutrition and Natural Products, Migal - Galilee Research Institute, Kiryat Shmona, Israel.
Nirit EzovDepartment of Nutrition and Natural Products, Migal - Galilee Research Institute, Kiryat Shmona, Israel.
Ofer DanayDepartment of Nutrition and Natural Products, Migal - Galilee Research Institute, Kiryat Shmona, Israel.
Ali KhattibDepartment of Nutrition and Natural Products, Migal - Galilee Research Institute, Kiryat Shmona, Israel.
Ron SchweitzerDepartment of Nutrition and Natural Products, Migal - Galilee Research Institute, Kiryat Shmona, Israel.
Soliman KhatibDepartment of Nutrition and Natural Products, Migal - Galilee Research Institute, Kiryat Shmona, Israel.
Jamal MahajnaDepartment of Nutrition and Natural Products, Migal - Galilee Research Institute, Kiryat Shmona, Israel.
Migal - Galilee Technology Center · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tropomyosin receptor kinase B (TrkB) serves as a pivotal factor in various cancers. To identify novel natural compounds with TrkB-inhibiting properties, a screening approach was applied using extracts from a collection of wild and cultivated mushroom fruiting bodies, and Ba/F3 cells that ectopically express TrkB (TPR-TrkB). We selected mushroom extracts that selectively inhibited proliferation of the TPR-TrkB cells. We then evaluated the ability of exogenous interleukin 3 to rescue growth inhibition by the selected TrkB-positive extracts. An ethyl acetate extract of

Indexed as

Auricularia auricula-Judae mushroomCancerKinase inhibitionTropomyosin receptor kinase B (TrkB)

Identifiers

PMID36895384
PMCPMC9988514
OpenAlexW4321113540

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.