Evidence map›Paper›PMID 36894936›Full record

Observational studyBMC musculoskeletal disorders2023

Association of spinopelvic index with proximal junctional failure developing in adult spinal deformity after surgical treatment: an observational study.

Zifang Zhang, Shang Chen, Shu Jia, Renchang Chen, Nianhu Li, Chunyang Meng

Abstract readObservational Study
In one paragraph

Observational study in BMC musculoskeletal disorders, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Zifang ZhangAffiliated hospital of Jining Medical University, Jining Medical University, No. 89, Guhuai Road, Jining, 272007, China. zhangzifang2002@163.com.
Shang ChenAffiliated hospital of Jining Medical University, Jining Medical University, No. 89, Guhuai Road, Jining, 272007, China.
Shu JiaAffiliated hospital of Jining Medical University, Jining Medical University, No. 89, Guhuai Road, Jining, 272007, China.
Renchang ChenOrthopedic Department of Shandong University of Traditional Chinese Medicine, No. 16369, Jingshi Road, Jinan, 250014, China.
Nianhu LiOrthopedic Department of Shandong University of Traditional Chinese Medicine, No. 16369, Jingshi Road, Jinan, 250014, China. tigerlee073@126.com.
Chunyang MengAffiliated hospital of Jining Medical University, Jining Medical University, No. 89, Guhuai Road, Jining, 272007, China. mengchunyang1600@mail.jnmc.edu.cn.

Funding

National Natural Science Foundation of China 81974345Natural Science Foundation of Shandong Province ZR2019MH044The Key Project of Shandong Geriatric Association LKJGG2021Z009the postdoctoral research project of the affiliated hospital of Jining Medical University 321210
6 · The paper itself

Abstract

backgroundThose pelvic parameters of sacral slope (SS) and pelvic tilt (PT) correlated significantly to lumbar spine and hip joints respectively. We proposed the match between SS and PT, namely spinopelvic index (SPI), in order to investigate whether the SPI correlated to proximal junctional failure (PJF) in adult spinal deformity (ASD) after correction surgery.

methodsNinety-nine ASD patients who had undergone long-fusion (≥ 5 vertebras) surgeries were reviewed retrospectively in two medical institutions from January 2018 to December 2019. Those SPI were calculated with the equation: SPI = SS/PT, and analyzed using the receiver operating characteristic curve (ROC) analysis. All participants were subdivided into the observational and control group. Comparisons of demographics, surgical and radiographic data between the two groups were performed. A Kaplan-Meier curve and log-rank test was used to analyze the differences in PJF-free survival time, and the 95% confidence intervals (CI) were recorded respectively.

resultsNineteen patients suffering from PJF had much smaller postoperative SPI (P = 0.015), but much larger TK postoperatively (P < 0.001). ROC analysis determined the best cutoff value of 0.82 for SPI (sensitivity = 88.5%, specificity = 57.9%; AUC = 0.719, 95%CI: 0.612-0.864; P = 0.003). There were 19 and 80 cases in the observational (SPI ≤ 0.82) and control group (SPI > 0.82) respectively. The incidence of PJF in the observational group was much higher (11/19 VS 8/80, P < 0.001); further logistic regression analysis showed that SPI ≤ 0.82 was associated with increased odds of PJF (odds ratio: 12.375; 95%CI: 3.851-39.771). PJF-free survival time in the observational group decreased significantly (P < 0.001, log-rank test), moreover, multivariate analysis demonstrated that a value of SPI ≤ 0.82 (HR 6.626, 95%CI: 1.981-12.165) was significantly associated with PJF.

conclusionsFor ASD patients underwent long-fusion surgeries, the SPI should be over 0.82. The incidence of PJF may increase by 12-fold in such individuals with the immediate SPI ≤ 0.82 postoperatively.

Indexed as

KyphosisSpinal FusionAdultHumansIncidenceLumbar VertebraePostoperative ComplicationsRetrospective StudiesSacrumAdult spinal deformityLong-fusion surgeryProximal junction failureSpinopelvic index

Identifiers

PMID36894936
PMCPMC9999581

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