Evidence map›Paper›PMID 36894320›Full record

ArticleeNeuro2023

Persistent Firing in Hippocampal CA1 Pyramidal Cells in Young and Aged Rats.

Yacine Brahimi, Beate Knauer, Alan Tobias Price, Maria Jesus Valero-Aracama, Antonio Reboreda, Magdalena Sauvage, Motoharu Yoshida

Open access · goldAbstract read
In one paragraph

Article in eNeuro, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
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  6. Estimation of cAMP binding in hippocampus CA1 field by a fluorescent probe.Frontiers in cell and developmental biology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Yacine BrahimiGerman Center for Neurodegenerative Diseases (DZNE), Magdeburg 39120, Germany.ORCID 0000-0002-4211-9662
Beate KnauerInternational Graduate School of Neuroscience (IGSN), Ruhr University Bochum (RUB), Bochum 44801, Germany.
Alan Tobias PriceGerman Center for Neurodegenerative Diseases (DZNE), Magdeburg 39120, Germany.
Maria Jesus Valero-AracamaFaculty of Psychology, Mercator Research Group-Structure of Memory, Ruhr University Bochum, Bochum 44801, Germany.
Antonio ReboredaGerman Center for Neurodegenerative Diseases (DZNE), Magdeburg 39120, Germany.
Magdalena SauvageOtto-von-Guericke Universität (OvGU), Medical Faculty, Magdeburg 39120, Germany.
Motoharu YoshidaGerman Center for Neurodegenerative Diseases (DZNE), Magdeburg 39120, Germany motoharu.yoshida@lin-magdeburg.de.
German Center for Neurodegenerative Diseases · DECenter for Behavioral Brain Sciences · DERuhr University Bochum · DEUniversity Hospitals of the Ruhr-University of Bochum · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Persistent neuronal firing is often observed in working memory and temporal association tasks both in humans and animals, and is believed to retain necessary information in these tasks. We have reported that hippocampal CA1 pyramidal cells are able to support persistent firing through intrinsic mechanisms in the presence of cholinergic agonists. However, it still remains largely unknown how persistent firing is affected by the development of animals and aging. Using

Indexed as

HippocampusPyramidal CellsAction PotentialsAnimalsChild, PreschoolCholinergic AgentsHumansNeuronsRatsCholinergic Agentsafterhyperpolarizationaged ratscholinergic agonistdepolarization currenthippocampuspersistent firing

Identifiers

PMID36894320
PMCPMC10062487
OpenAlexW4323657063

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.