Evidence map›Paper›PMID 36894011›Full record

Trial reportBrazilian journal of anesthesiology (Elsevier)

The association of hemoglobin with postoperative delirium and atrial fibrillation after cardiac surgery: a retrospective sub-study.

Sinem Sari, Jack Brooker, Mateo Montalvo-Campana, Peter Shehata, Xuan Pu, Steven Insler, Kurt Ruetzler, Christopher A Troianos, Alparslan Turan

Open access · diamondAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Brazilian journal of anesthesiology (Elsevier). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
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  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 2 countries.

Sinem SariCleveland Clinic, Anesthesiology Institute, Department of Outcomes Research, Cleveland, Ohio; Adnan Menderes University, Department of General Anesthesiology, Aydın, Turkey.
Jack BrookerCleveland Clinic, Anesthesiology Institute, Department of Outcomes Research, Cleveland, Ohio.
Mateo Montalvo-CampanaCleveland Clinic, Anesthesiology Institute, Department of Outcomes Research, Cleveland, Ohio.
Peter ShehataCleveland Clinic, Anesthesiology Institute, Department of General Anesthesiology, Cleveland, Ohio.
Xuan PuCleveland Clinic, Department of Quantitative Health Sciences, Cleveland, Ohio.
Steven InslerCleveland Clinic, Anesthesiology Institute, Department of Intensive Care & Resuscitation, Cleveland, Ohio.
Kurt RuetzlerCleveland Clinic, Anesthesiology Institute, Department of Outcomes Research, Cleveland, Ohio; Cleveland Clinic, Anesthesiology Institute, Department of General Anesthesiology, Cleveland, Ohio.
Christopher A TroianosCleveland Clinic, Anesthesiology Institute, Cleveland, Ohio.
Alparslan TuranCleveland Clinic, Anesthesiology Institute, Department of Outcomes Research, Cleveland, Ohio; Cleveland Clinic, Anesthesiology Institute, Department of General Anesthesiology, Cleveland, Ohio. Electronic address: turana@ccf.org.
Cleveland Clinic · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMost cardiac surgery patients experience postoperative anemia. Delirium and Atrial Fibrillation (AF) are common and independent predictors of morbidity and mortality. Few reports examine their association with postoperative anemia. This study aims to quantify the association between anemia and these outcomes in patients undergoing cardiac surgery.

methodsThis post-hoc analysis of the DECADE randomized controlled trial ran at six academic US hospitals. Patients aged 18-85 years with heart rate > 50 bpm undergoing cardiac surgery who had daily hemoglobin measurements in the first 5 Postoperative Days (POD) were included. Delirium was assessed twice daily with the Confusion Assessment Method for the ICU (CAM - ICU), preceded by the Richmond Agitation and Sedation Scale, with patients excluded from assessment if sedated. Patients had daily hemoglobin measurements, continuous cardiac monitoring plus twice-daily 12-lead electrocardiograms, up to POD4. AF was diagnosed by clinicians blinded to hemoglobin levels.

resultsFive hundred and eighty-five patients were included. Mean postoperative hemoglobin Hazard Ratio (HR): 0.99 (95% CI 0.83, 1.19; p = 0.94) per 1 g.dL

conclusionsMost patients undergoing major cardiac surgery were anemic in the postoperative phase. AF and delirium occurred in 34% and 12% of patients, respectively, but neither were significantly correlated with postoperative hemoglobin.

Indexed as

AnemiaAtrial FibrillationCardiac Surgical ProceduresDeliriumHemoglobinsPostoperative ComplicationsAdolescentAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedRetrospective StudiesYoung AdultHemoglobinsAnemiaAtrial fibrillationCardiac surgeryDeliriumGeneral anesthesia

Identifiers

PMID36894011
PMCPMC11148484
OpenAlexW4323353598

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.