ArticleEuropean heart journal. Quality of care & clinical outcomes2023
Alerting trends in epidemiology for calcific aortic valve disease, 1990-2019: An age-period-cohort analysis for the Global Burden of Disease Study 2019.
Article in European heart journal. Quality of care & clinical outcomes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Meta-Analysis Global Group in Chronic Heart Failure score for the prediction of mortality in valvular heart disease.ESC heart failure · 2024Pooled it
- Trends and Projections for Aortic Stenosis and Hypertension-Related Mortality Among Older Adults in the United States: A Retrospective Population-Based Analysis.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2026Article
- Cyclic guanosine monophosphate-protein kinase G signaling attenuates aortic valve calcification through ULK1-mediated autophagy.Signal transduction and targeted therapy · 2026Article
- Association of triglyceride-glucose and obesity-derived indices with the risk of aortic stenosis among individuals in cardiovascular-kidney-metabolic syndrome stages 0-3: a prospective cohort study from the UK Biobank.Frontiers in endocrinology · 2026Article
- Metformin mitigates aortic valve degeneration in an ex vivo three-dimensional tissue model.Scientific reports · 2025Article
- Changing trends in burden of calcific aortic valve diseases and degenerative mitral valve diseases among people aged 60-89 years from 1990 to 2030.European journal of medical research · 2025Article
- Trends and projections of heart failure among adolescents and young adults: an in-depth analysis for the Global Burden of Disease Study 2021.European heart journal. Quality of care & clinical outcomes · 2025Article
- Global, regional, and national burden of nonrheumatic calcific aortic valve disease based on GBD study 2021.Scientific reports · 2025Article
- The Challenge in Burden of Pulmonary Arterial Hypertension: A Perspective From the Global Burden of Disease Study.MedComm · 2025Article
- Global, regional, and national time trends in mortality for breast cancer, 1992-2021: an age-period-cohort analysis for the global burden of disease 2021 study.BMC public health · 2025Article
- 2025 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Association.Circulation · 2025Review
- Long-term trends in the burden of non-rheumatic calcific aortic valve disease in China from 1990 to 2021, with projections to 2050: results from the global burden of disease study.Frontiers in medicine · 2025Article
- Global trends in refractive disorders from 1990 to 2021: insights from the global burden of disease study and predictive modeling.Frontiers in public health · 2025Article
- Significance of APOB/APOA1 Ratio in the Prediction of Calcific Aortic Valve Disease.Cardiovascular therapeutics · 2025Article
- Global, regional, and national burden of non-rheumatic valvular heart disease and Its projections to 2035: comprehensive analysis of the global burden of disease study 2019.Frontiers in cardiovascular medicine · 2025Article
- Exploring the Prognostic Role of Red Blood Cell Distribution Width in Aortic Valve Calcification Evaluations via Multi-Slice Computed Tomography.Reviews in cardiovascular medicine · 2024Article
- Article
- 2024 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Association.Circulation · 2024Review
- Assessment of cardio-renal-hepatic function in patients with valvular heart disease: a multi-biomarker approach-the cardio-renal-hepatic score.BMC medicine · 2023Article
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Abstract
aimsTo assess the trends in calcific aortic valve disease (CAVD) epidemiology, with an emphasis on CAVD mortality, leading risk factors, and their associations with age, period, and birth cohort. METHODS AND
resultsPrevalence, disability-adjusted life years, and mortality were derived from the Global Burden of Disease Study 2019. The age-period-cohort model was employed to study the detailed trends of CAVD mortality and its leading risk factors. Globally, CAVD showed unsatisfactory results from 1990 to 2019, with the CAVD deaths of 127 000 in 2019. CAVD mortality was substantially reduced in high socio-demographic index (SDI) countries [-1.45%, 95% confidence interval (CI) (-1.61 to -1.30)], mildly increased in high-middle SDI countries [0.22%, 95% CI (0.06-0.37)], and unchanged in other SDI quintiles. There was a noticeable transition in CAVD deaths from younger to older populations globally. The CAVD mortality increased exponentially with age, and the male had higher mortality than the female before 80 years old. Favourable period [0.69, 95% CI (0.66-0.72)] and birth effects [0.30, 95% CI (0.22-0.43)] were mainly observed in high SDI countries, while unfavourable effects were mostly noticed in high-middle SDI countries. High systolic blood pressure was the leading risk factor of CAVD deaths globally, and it showed favourable trends in high SDI regions.
conclusionAlthough CAVD mortality reduction was observed globally, unfavourable period, and cohort effects were found in many countries. Increase of mortality rate among the population ≥85 years was the common challenge across all SDI quintiles, stressing the necessity to further improve health care for CAVD patients worldwide.
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