Evidence map›Paper›PMID 36893448›Full record

ReviewThe journal of physical chemistry. B2023

Singlet Molecular Oxygen: from COIL Lasers to Photodynamic Cancer Therapy.

S J Davis, Y Zhao, T C Yu, E V Maytin, S Anand, T Hasan, B W Pogue

Open access · greenAbstract readReview
In one paragraph

Review in The journal of physical chemistry. B, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Understanding mechanisms of antioxidant action in health and disease.Nature reviews. Molecular cell biology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

S J DavisPhysical Sciences Inc., 20 New England Business Center, Andover, Massachusetts 01810, United States.ORCID 0000-0002-2124-5977
Y ZhaoPhysical Sciences Inc., 20 New England Business Center, Andover, Massachusetts 01810, United States.
T C YuPhysical Sciences Inc., 20 New England Business Center, Andover, Massachusetts 01810, United States.
E V MaytinDepartments of Biomedical Engineering and Dermatology, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, Ohio 44195, United States.
S AnandDepartments of Biomedical Engineering and Dermatology, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, Ohio 44195, United States.
T HasanWellman Center for Photomedicine, 40 Blossom Street, BAR 314A, Boston, Massachusetts 02114, United States.ORCID 0000-0003-0871-6057
B W PogueDepartment of Medical Physics, Wisconsin Institutes for Medical Research, 1111 Highland Avenue, Madison, Wisconsin 53705, United States.
Physical Sciences (United States) · USCleveland Clinic · USWisconsin Institutes for Discovery · US

Funding

Small Molecule Enhancers of Photodynamic Therapy for Skin CancerP01CA084203 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI Brian William Pogue · 2001 to 2026
$27.9M
Ultra-sensitive Singlet Oxygen Dosimeter for Skin Cancer Treatment and PreventionR44CA250727 · NCI · PHYSICAL SCIENCES, INC · PI ZHAO, YOUBO · 2020 to 2022
$2.2M
Real Time, Automated Singlet Oxygen Dosimeter for PDTR44CA128364 · NCI · PHYSICAL SCIENCES, INC · PI DAVIS, STEVEN J · 2007 to 2009
$1.2M
Singlet Oxygen Detector for Photodynamic TherapyR44CA096243 · NCI · PHYSICAL SCIENCES, INC · PI DAVIS, STEVEN J · 2003 to 2004
$754k
NCI NIH HHS P01 CA084203NCI NIH HHS R44 CA096243NCI NIH HHS R44 CA128364NCI NIH HHS R44 CA250727
6 · The paper itself

Abstract

Translation of experimental techniques from one scientific discipline to another is often difficult but rewarding. Knowledge gained from the new area can lead to long lasting and fruitful collaborations with concomitant development of new ideas and studies. In this Review Article, we describe how early work on the chemically pumped atomic iodine laser (COIL) led to the development of a key diagnostic for a promising cancer treatment known as photodynamic therapy (PDT). The highly metastable excited state of molecular oxygen, a

Indexed as

NeoplasmsPhotochemotherapyAnimalsIodineLasersMicePhotosensitizing AgentsSinglet OxygenIodinePhotosensitizing AgentsSinglet Oxygen

Identifiers

PMID36893448
PMCPMC11209853
OpenAlexW4323657427

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.