Evidence map›Paper›PMID 36893445›Full record

ArticleOcular immunology and inflammation2024

Dual-Energy X-Ray Absorptiometry Scan Utilization and Skeletal Fragility Among Non-Infectious Uveitis Patients Exposed to Oral Glucocorticoids.

Nicholas J Butler, Devin Cohen, Yinxi Yu, John H Kempen, Lucia Sobrin, Brian L VanderBeek

Abstract read
In one paragraph

Article in Ocular immunology and inflammation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nicholas J ButlerVeterans Affairs Boston Healthcare System, Surgical Service, Boston, Massachusetts, USA.
Devin CohenScheie Eye Institute, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Yinxi YuCenter for Preventive Ophthalmology and Biostatistics, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
John H KempenMassachusetts Eye and Ear, Harvard Medical School, Department of Ophthalmology, Boston, Massachusetts, USA.ORCID 0000-0002-2967-4792
Lucia SobrinMassachusetts Eye and Ear, Harvard Medical School, Department of Ophthalmology, Boston, Massachusetts, USA.ORCID 0000-0003-1575-0819
Brian L VanderBeekScheie Eye Institute, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0003-4953-118X

Funding

Scientific TransparencyP30EY001583 · NEI · UNIVERSITY OF PENNSYLVANIA · PI CLAIRE H MITCHELL · 1985 to 2026
$19.5M
Identifying Protective and Risk Factors for Non-infectious UveitisR21EY029851 · NEI · MASSACHUSETTS EYE AND EAR INFIRMARY · PI SOBRIN, LUCIA · 2019 to 2020
$469k
NEI NIH HHS P30 EY001583NEI NIH HHS R21 EY029851
6 · The paper itself

Abstract

introductionCurrently, little is known regarding bone health surveillance for glucocorticoid-exposed non-infectious uveitis (NIU) patients or their baseline risks of skeletal fragility outcomes.

methodsUsing claims data, we calculated rates of dual-energy x-ray absorptiometry (DXA) screening for glucocorticoid-exposed NIU and rheumatoid arthritis (RA) patients. Separately, we compared risks of skeletal fragility metrics amongst NIU patients, RA patients, and controls, independent of glucocorticoid use.

resultsThe adjusted hazard ratio (aHR) of NIU patients to have a DXA scan was 0.64 (95% CI, 0.63-0.65;

conclusionsNIU patients are 36% less likely to receive a DXA scan after high-dose glucocorticoid exposure compared with RA patients. No elevated risk of osteoporosis for NIU patients was found compared to normal controls.

Indexed as

Absorptiometry, PhotonGlucocorticoidsOsteoporosisUveitisAdministration, OralAdultAgedArthritis, RheumatoidBone DensityFemaleHumansMaleMiddle AgedRetrospective StudiesYoung AdultGlucocorticoidsBisphosphonatesdual-energy x-ray absorptiometry (DXA)glucocorticoidsocular inflammatory diseaseosteopeniaosteoporosispathologic fracturerheumatoid arthritisuveitis

Identifiers

PMID36893445
PMCPMC10491740

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.