Evidence map›Paper›PMID 36893271›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

Aneuploidy and gene dosage regulate filamentation and host colonization by

Pallavi Kakade, Shabnam Sircaik, Corinne Maufrais, Iuliana V Ene, Richard J Bennett

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 30 citations in OpenAlex.

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  9. The pathogenicity and future treatment strategies ofFrontiers in cellular and infection microbiology · 2026
    Review
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  19. ControllingInfection and immunity · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Pallavi KakadeMolecular Microbiology and Immunology Department, Brown University, Providence, RI 02912.ORCID 0000-0003-0388-9012
Shabnam SircaikMolecular Microbiology and Immunology Department, Brown University, Providence, RI 02912.ORCID 0000-0003-4553-6901
Corinne MaufraisInstitut Pasteur Bioinformatic Hub, Université Paris Cité, Paris 75015, France.ORCID 0000-0002-8718-0432
Iuliana V EneInstitut Pasteur, Université Paris Cité, Fungal Heterogeneity Lab, Paris 75015, France.
Richard J BennettMolecular Microbiology and Immunology Department, Brown University, Providence, RI 02912.ORCID 0000-0001-7563-484X
Brown University · USInstitut Pasteur · FR

Funding

Transcriptional Regulation of C. albicans Cell Fate and Host InteractionsR01AI081704 · NIAID · BROWN UNIVERSITY · PI Richard John Bennett · 2010 to 2026
$6.4M
Commensal Candida albicans primed Th17 immunityR01AI168222 · NIAID · CINCINNATI CHILDRENS HOSP MED CTR · PI Richard John Bennett, Sing Sing Way · 2023 to 2026
$3.1M
Genetic Regulation of Heritable Switching in Candida albicansR01AI141893 · NIAID · BROWN UNIVERSITY · PI BENNETT, RICHARD JOHN · 2019 to 2023
$2.7M
To Define the Role of C. albicans Candidalysin in the Gastrointestinal NicheR21AI166869 · NIAID · BROWN UNIVERSITY · PI BENNETT, RICHARD JOHN · 2021 to 2022
$438k
NIAID NIH HHS R01 AI081704NIAID NIH HHS R01 AI141893NIAID NIH HHS R01 AI168222NIAID NIH HHS R21 AI166869
6 · The paper itself

Abstract

Aneuploidy is a frequent occurrence in fungal species where it can alter gene expression and promote adaptation to a variety of environmental cues. Multiple forms of aneuploidy have been observed in the opportunistic fungal pathogen

Indexed as

Candida albicansGastrointestinal TractAneuploidyFungal ProteinsGene DosageGene Expression Regulation, FungalHumansFungal Proteinsadaptationcommensalismfitnesskaryotypemycology

Identifiers

PMID36893271
PMCPMC10089209
OpenAlexW4323656748

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.