Evidence map›Paper›PMID 36893270›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

The

Jeffrey Duncan-Lowey, Emerson Crabill, Abigail Jarret, Shawna C O Reed, Craig R Roy

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 13 citations in OpenAlex.

  1. bioRxiv : the preprint server for biology · 2026
    Article
  2. mLife · 2026
    Article
  3. Review
  4. Review
  5. Review
  6. A diverse family of bacterial deubiquitinases is defined by theProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  7. Article
  8. Bacterial Puppeteering: How the Stealth BacteriumPathogens (Basel, Switzerland) · 2025
    Review
  9. Article
  10. Article
  11. Identification of aInfection and immunity · 2025
    Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jeffrey Duncan-LoweyDepartment of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT 06536.ORCID 0000-0002-3615-9596
Emerson CrabillDepartment of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT 06536.ORCID 0000-0001-9886-8550
Abigail JarretDepartment of Immunobiology, Yale University School of Medicine, New Haven, CT 06536.
Shawna C O ReedDepartment of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT 06536.ORCID 0000-0002-9041-4869
Craig R RoyDepartment of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT 06536.
Yale University · US

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM007205 · NIGMS · YALE UNIVERSITY · PI KAZMIERCZAK, BARBARA I · 1985 to 2019
$42.9M
Biogenesis of the Coxiella-containing vacuoleR01AI114760 · NIAID · YALE UNIVERSITY · PI ROY, CRAIG R. · 2015 to 2019
$2.1M
Modulation of Host Cell Functions by Coxiella burnetiiR01AI064559 · NIAID · YALE UNIVERSITY · PI ROY, CRAIG R. · 2006 to 2010
$1.8M
Defining epistatic interactions among Coxiella burnetii effector proteins using a CRISPRi approachR21AI171333 · NIAID · YALE UNIVERSITY · PI ROY, CRAIG R. · 2022 to 2023
$461k
NIAID NIH HHS R01 AI064559NIAID NIH HHS R01 AI114760NIAID NIH HHS R21 AI171333NIGMS NIH HHS T32 GM007205
6 · The paper itself

Abstract

Eukaryotes have cytosolic surveillance systems to detect invading microorganisms and initiate protective immune responses. In turn, host-adapted pathogens have evolved strategies to modulate these surveillance systems, which can promote dissemination and persistence in the host. The obligate intracellular pathogen

Indexed as

Coxiella burnetiiAnimalsBacterial ProteinsBacterial Secretion SystemsDeubiquitinating EnzymesHost-Pathogen InteractionsMammalsUbiquitinsBacterial ProteinsBacterial Secretion SystemsDeubiquitinating EnzymesUbiquitinsbacterial effectorsinnate immunitytype IV secretion

Identifiers

PMID36893270
PMCPMC10089202
OpenAlexW4323656701

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.