SynthesisJMIR public health and surveillance2023
Willingness to Vaccinate Against Herpes Zoster and Its Associated Factors Across WHO Regions: Global Systematic Review and Meta-Analysis.
Synthesis in JMIR public health and surveillance, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
50 citing papers in PubMed, 2 syntheses or guidelines pooled it, 70 citations in OpenAlex.
- Human papillomavirus and vaccine knowledge, willingness, and uptake among university students: a systematic review and meta-analysis.BMC public health · 2025Pooled it
- Evaluating the efficacy of machine learning in predicting postherpetic neuralgia: a systematic review and meta-analysis.Frontiers in neurology · 2025Pooled it
- Quantitative study of the knowledge, attitudes, and practices (KAP) towards herpes zoster (HZ) and HZ vaccination: Survey findings from a multi-country study in Asia (ZOASIS).Human vaccines & immunotherapeutics · 2026Article
- Post-marketing safety surveillance of Haemophilus influenzae Type b conjugate vaccine in children aged 3 months to 5 years in Jiangsu, China.Human vaccines & immunotherapeutics · 2026Observational
- Herpes zoster knowledge, attitudes, and herpes zoster vaccine acceptability among patients in a tertiary hospital and dermatologists in the Philippines: A cross-sectional study.Human vaccines & immunotherapeutics · 2026Article
- Herpes zoster vaccination among older adults in urban China: A mixed-methods study in Shenzhen.Human vaccines & immunotherapeutics · 2026Article
- Knowledge of Herpes Zoster and Attitudes Toward Vaccination: A Questionnaire-Based Study in Outpatient and Online Settings.Vaccines · 2026Article
- Profiles of Hesitancy Toward the Herpes Zoster Vaccine Among Older Adults in China: A Latent Profile Analysis.Vaccines · 2026Article
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- Progressive Improvements with Repeated High-Concentration Capsaicin Patch: Real-World Data from the Retrospective CASPAR German Pain e-Registry Study in Postherpetic Neuralgia.Dermatology and therapy · 2026Article
- Analysis of the characteristics of parents' reasons for refusing HPV vaccination for their daughters: a cross-sectional study.BMC public health · 2026Article
- Willingness and influencing factors of herpes zoster vaccination intention among Chinese residents: a study based on framing effects.Frontiers in public health · 2026Article
- Development of a herpes zoster vaccination intention scale and identification of factors associated with vaccine hesitancy among middle-aged and older attendees in community health centers: A Protection Motivation Theory based study.Human vaccines & immunotherapeutics · 2025Article
- Herpes zoster vaccination and vaccine preferences among persons aged 50-64 years in Australia: Findings from a discrete choice experiment.Human vaccines & immunotherapeutics · 2025Article
- Willingness to pay for herpes zoster vaccination in urban China.Human vaccines & immunotherapeutics · 2025Article
- Trends and determinants of 23-valent pneumococcal polysaccharide vaccine revaccination among older adults in Shanghai, China, 2013-2023: A database-based study.Human vaccines & immunotherapeutics · 2025Article
- Preferences for and drivers of adult vaccination clinic site selection: A cross-sectional study in 30 provinces in China.Human vaccines & immunotherapeutics · 2025Article
- Patient preferences toward herpes zoster vaccination among individuals aged 50 years or older in South Korea: Findings from a discrete choice experiment.Human vaccines & immunotherapeutics · 2025Article
- Surveillance on the coverage of herpes zoster vaccine and post-marketing adverse events in Jiangsu province, China.Human vaccines & immunotherapeutics · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundA life-course immunization approach would enhance the quality of life across all age groups and improve societal well-being. The herpes zoster (HZ) vaccine is highly recommended for older adults to prevent HZ infection and related complications. The proportions of willingness to receive the HZ vaccine varies across countries, and various kinds of factors, including sociodemographics and individual perceptions, influence the willingness to vaccinate.
objectiveWe aim to estimate the HZ vaccination willingness rate and identify factors associated with vaccine uptake willingness across all World Health Organization (WHO) regions.
methodsA global systematic search was performed on PubMed, Web of Science, and the Cochrane Library for all papers related to the HZ vaccine published until June 20, 2022. Study characteristics were extracted for each included study. Using double arcsine transformation, vaccination willingness rates with 95% CIs were pooled and reported. The willingness rate and associated factors were analyzed by geographical context. Associated factors were also summarized based on Health Belief Model (HBM) constructs.
resultsOf the 26,942 identified records, 13 (0.05%) papers were included, covering 14,066 individuals from 8 countries in 4 WHO regions (Eastern Mediterranean Region, European Region, Region of the Americas, and Western Pacific Region). The pooled vaccination willingness rate was 55.74% (95% CI 40.85%-70.13%). Of adults aged ≥50 years, 56.06% were willing to receive the HZ vaccine. After receiving health care workers' (HCWs) recommendations, 75.19% of individuals were willing to get the HZ vaccine; without HCWs' recommendations, the willingness rate was only 49.39%. The willingness rate was more than 70% in the Eastern Mediterranean Region and approximately 55% in the Western Pacific Region. The willingness rate was the highest in the United Arab Emirates and the lowest in China and the United Kingdom. The perception of HZ severity and susceptibility was positively associated with vaccination willingness. The perceived barriers to vaccination willingness (main reasons for unwillingness) included low trust in the effectiveness of the HZ vaccine, concerns about safety, financial concerns, and being unaware of the HZ vaccine's availability. Older individuals, those having lower education, or those having lower income levels were less likely to willing to be vaccinated.
conclusionsOnly 1 in 2 individuals showed a willingness to be vaccinated against HZ. The willingness rate was the highest in the Eastern Mediterranean Region. Our findings show the critical role HCWs play in promoting HZ vaccination. Monitoring HZ vaccination willingness is necessary to inform public health decision-making. These findings provide critical insights for designing future life-course immunization programs.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.