Evidence map›Paper›PMID 36892908›Full record

ArticleAmerican journal of physiology. Renal physiology2023

A novel mouse model for an inducible gene modification in the renal thick ascending limb.

Laurent Bourqui, Denise V Winter, Alex Odermatt, Dominique Loffing-Cueni, Johannes Loffing

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of physiology. Renal physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Guidelines on antibody use in physiology research.American journal of physiology. Renal physiology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Laurent BourquiInstitute of Anatomy, University of Zurich, Zurich, Switzerland.ORCID 0000-0003-0985-7337
Denise V WinterDivision of Molecular and Systems Toxicology, Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland.ORCID 0000-0002-3764-1747
Alex OdermattDivision of Molecular and Systems Toxicology, Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland.ORCID 0000-0002-6820-2712
Dominique Loffing-CueniInstitute of Anatomy, University of Zurich, Zurich, Switzerland.
Johannes LoffingInstitute of Anatomy, University of Zurich, Zurich, Switzerland.ORCID 0000-0002-9415-6588
University of Zurich · CHUniversity of Basel · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The thick ascending limb (TAL) is critical for renal control of fluid and ion homeostasis. The function of the TAL depends on the activity of the bumetanide-sensitive Na

Indexed as

KidneySodium-Potassium-Chloride SymportersAnimalsDisease Models, AnimalFemaleMaleMiceSodiumSolute Carrier Family 12, Member 1Slc12a1 protein, mouseSodiumSodium-Potassium-Chloride SymportersSolute Carrier Family 12, Member 1Ai14 and mT/mG reporter micecell lineage tracingCre immunostainingNa+-K+-2Cl− cotransporterthin limbs

Identifiers

PMID36892908
PMCPMC10085568
OpenAlexW4323652170

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.