Evidence map›Paper›PMID 36892790›Full record

ArticleVeterinary research communications2023

Phytochemicals, antimicrobial, and sporicidal activities of moss, Dicranum polysetum Sw., against certain honey bee bacterial pathogens.

Şengül Alpay Karaoğlu, Nurettin Yayli, Rahşan Akpinar, Arif Bozdeveci, İshak Erik, Şeyma Suyabatmaz, Büşra Korkmaz, Nevzat Batan, Selma Kaya, Cevat Nisbet and 1 more

Abstract read
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Article in Veterinary research communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
3.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Şengül Alpay KaraoğluDepartment of Biology, Faculty of Arts and Sciences, Recep Tayyip Erdoğan University, Rize, 53100, Turkey. sengul.karaoglu@erdogan.edu.tr.ORCID http://orcid.org/0000-0003-1047-8350
Nurettin YayliDepartment of Pharmacognosy, Faculty of Pharmacy, Karadeniz Technical University, Trabzon, 61080, Turkey.ORCID http://orcid.org/0000-0003-4174-3014
Rahşan AkpinarLaboratory of Bee Diseases, Samsun Veterinary Control Institute, Samsun, 55200, Turkey.ORCID http://orcid.org/0000-0003-0075-9247
Arif BozdeveciDepartment of Biology, Faculty of Arts and Sciences, Recep Tayyip Erdoğan University, Rize, 53100, Turkey.ORCID http://orcid.org/0000-0002-0729-9143
İshak ErikDepartment of Pharmacognosy, Faculty of Pharmacy, Karadeniz Technical University, Trabzon, 61080, Turkey.ORCID http://orcid.org/0000-0002-9729-1013
Şeyma SuyabatmazDepartment of Biology, Faculty of Arts and Sciences, Recep Tayyip Erdoğan University, Rize, 53100, Turkey.ORCID http://orcid.org/0000-0001-8597-3650
Büşra KorkmazDepartment of Pharmacognosy, Faculty of Pharmacy, Karadeniz Technical University, Trabzon, 61080, Turkey.ORCID http://orcid.org/0000-0002-3747-8855
Nevzat BatanMolecular Biology and Genetics, Karadeniz Technical University, Trabzon, 61080, Turkey.ORCID http://orcid.org/0000-0001-8456-5719
Selma KayaLaboratory of Bee Diseases, Samsun Veterinary Control Institute, Samsun, 55200, Turkey.ORCID http://orcid.org/0000-0002-8934-3418
Cevat NisbetDepartment of Biochemistry, Faculty of Veterinary Medicine, Ondokuz Mayıs University, Samsun, 55200, Turkey.ORCID http://orcid.org/0000-0002-7042-4605
Ahmet GülerDepartment of Animal Science, Faculty of Agriculture, Ondokuz Mayıs University, Samsun, 55200, Turkey.ORCID http://orcid.org/0000-0003-0167-2346
Karadeniz Technical University · TRRecep Tayyip Erdoğan University · TROndokuz Mayıs University · TRSamsun University · TR

Funding

Recep Tayyip Erdogan University Research Fund RTEÜ-FBA-2017-807Scientific and Technological Research Council of Turkey TUBITAK-TOVAG-118O415
6 · The paper itself

Abstract

Beekeeping is an important agricultural and commercial activity globally practiced. Honey bee is attacked by certain infectious pathogens. Most important brood diseases are bacterial including American Foulbrood (AFB), caused by Paenibacillus larvae (P. larvae), and European Foulbrood (EFB) by Melissococcus plutonius (M. plutonius) in addition of secondary invaders, e.g. Paenibacillus alvei (P. alvei) and Paenibacillus dendritiformis (P. dendritiformis). These bacteria cause the death of larvae in honey bee colonies. In this work, antibacterial activities of extracts, fractions, and isolated certain compounds (nominated 1-3) all originated from moss, Dicranum polysetum Sw. ( D. polysetum), were tested against some honey bee bacterial pathogens. Minimum inhibitory concentration, minimum bactericidal concentration, and sporicidal values ​​of methanol extract, ethyl acetate, and n-hexane fractions ranged between 10.4 and 18.98, 83.4-303.75 & 5.86-18.98 µg/mL against P. larvae, respectively. Antimicrobial activities of the ethyl acetate sub-fractions (fraction) and the isolated compounds (1-3) were tested against AFB- and EFB-causing bacteria. Bio-guided chromatographic separation of ethyl acetate fraction, a crude methanolic extract obtained from aerial parts of D. polysetum resulted in three natural compounds: a novel one, i.e. glycer-2-yl hexadeca-4-yne-7Z,10Z,13Z-trienoate (1, dicrapolysetoate; given as trivial name), in addition to two known triterpenoids poriferasterol (2), and γ-taraxasterol (3). Minimum inhibitory concentration ranges were 1.4-60.75, 8.12-65.0, 2.09-33.44 & 1.8-28.75 µg/mL for sub-fractions, compounds 1, 2, and 3, respectively.

Indexed as

Anti-Bacterial AgentsPhytochemicalsAcetatesAnimalsBeesLarvaPlant ExtractsAcetatesAnti-Bacterial Agentsethyl acetatePhytochemicalsPlant ExtractsAntimicrobial activityDicranum polysetumEuropean FoulbroodHoney bee larvaePaenibacillus larvae

Identifiers

PMID36892790
OpenAlexW4323652161

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.