Evidence map›Paper›PMID 36892770›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2023

DeepZ: A Deep Learning Approach for Z-DNA Prediction.

Nazar Beknazarov, Maria Poptsova

Abstract read
PubMed Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Formation and biological implications of Z-DNA.Trends in genetics : TIG · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Nazar BeknazarovLaboratory of Bioinformatics, Faculty of Computer Science, National Research University Higher School of Economics, Moscow, Russia.
Maria PoptsovaLaboratory of Bioinformatics, Faculty of Computer Science, National Research University Higher School of Economics, Moscow, Russia. mpoptsova@hse.ru.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Here we describe an approach that uses deep learning neural networks such as CNN and RNN to aggregate information from DNA sequence; physical, chemical, and structural properties of nucleotides; and omics data on histone modifications, methylation, chromatin accessibility, and transcription factor binding sites and data from other available NGS experiments. We explain how with the trained model one can perform whole-genome annotation of Z-DNA regions and feature importance analysis in order to define key determinants for functional Z-DNA regions.

Indexed as

Deep LearningDNA, Z-FormChromatinHistone CodeNeural Networks, ComputerChromatinDNA, Z-FormCNNDeep learningDNA secondary structuresMachine learningOmics dataRNNZ-DNA

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.