Evidence map›Paper›PMID 36892717›Full record

ArticleMedical oncology (Northwood, London, England)2023

The evolutionary cancer gene network theory versus embryogenic hypotheses.

Vladimir Florin Niculescu

Abstract read
PubMed Publisher
In one paragraph

Article in Medical oncology (Northwood, London, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Vladimir Florin NiculescuDiedorf, Augsburg, Bavaria, Germany. vladimir.niculescu@yahoo.com.ORCID http://orcid.org/0000-0002-0572-2585

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present paper compares the statements of the evolutionary cancer gene-network theory (cancer genome theory) with the statements of embryogenic hypotheses like the embryonic rest hypothesis, the very small embryonic-like stem cells hypothesis, (VSEL), the para-embryonic p-ESC hypothesis, and the PGCC-life cycle hypothesis, including the life code theory. In my opinion, the evolutionary gene network theory is the only theory that can satisfactorily explain the homologies between carcinogenesis, tumorigenesis, metastasis, gametogenesis, and early embryogenesis. From an evolutionary point of view, there is no reason to see the origin of cancer in cells of early embryonic life.

Indexed as

Gene Regulatory NetworksNeoplasmsCarcinogenesisEmbryonic DevelopmentHumansPolyploidyCSCsEvolutionMetastasisOncogenesisPGCCsPolyploidyTumorigenesis

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.