Evidence map›Paper›PMID 36892704›Full record

ReviewJournal of assisted reproduction and genetics2023

A review of the 2021/2022 PGDIS Position Statement on the transfer of mosaic embryos.

Norbert Gleicher, Lyka Mochizuki, David H Barad, Pasquale Patrizio, Raoul Orvieto, International Do No Harm Group in IVF (IDNHG-IVF)

Open access · greenAbstract readReviewConsensus Statement
In one paragraph

Review in Journal of assisted reproduction and genetics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
4.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Norbert GleicherThe Center for Human Reproduction, New York, NY, USA. ngleicher@thechr.com.ORCID http://orcid.org/0000-0002-0202-4167
Lyka MochizukiThe Center for Human Reproduction, New York, NY, USA.
David H BaradThe Center for Human Reproduction, New York, NY, USA.
Pasquale PatrizioThe Center for Human Reproduction, New York, NY, USA.
Raoul OrvietoChaim Sheba Medical Center, Infertility and IVF Unit, Department of Obstetrics and Gynecology, Tel Aviv University, Sackler Medical Faculty, Tel-Aviv, Israel.
International Do No Harm Group in IVF (IDNHG-IVF)
Foundation for Reproductive Medicine · USCenter for Human Reproduction · USTel Aviv University · ILUniversity of Miami · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The practice of preimplantation genetic testing for aneuploidy (PGT-A) in association with in vitro fertilization (IVF) since 2016 has been mostly directed by three highly controversial guidance documents issued by the Preimplantation Genetic Diagnosis International Society (PGDIS). Because these documents are so influential on worldwide IVF practice, the most recent one is here the subject of a detailed review, again revealing important misrepresentations and internal contradictions. Most importantly, however, this most recent guidance document still does not prevent the non-use and/or disposal of large numbers of embryos with substantial pregnancy and live-birth potential and, therefore, continues to propagate an IVF practice harmful to many infertile women.

Indexed as

Infertility, FemalePreimplantation DiagnosisAneuploidyBlastocystFemaleFertilization in VitroGenetic TestingHumansPregnancyEmbryo mosaicismGuidelinesIn vitro fertilization (IVF)Preimplantation genetic testing for aneuploid (PGT-a)

Identifiers

PMID36892704
PMCPMC10224891
OpenAlexW4323652484

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.