ArticleEuropean journal of physical and rehabilitation medicine2023
Lower-extremity constraint-induced movement therapy improved motor function, mobility, and walking after stroke.
Article in European journal of physical and rehabilitation medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.
- Global research hotspots and trends in constraint-induced movement therapy in rehabilitation over the past 30 years: a bibliometric and visualization study.Frontiers in neurology · 2024Pooled it
- Modified constraint-induced movement therapy for lower extremity intervention on patients with stroke: A Scoping Review.Sports medicine and health science · 2026Review
- Health-related quality of life following lower-extremity constraint-induced movement therapy after stroke: an intervention study.Frontiers in neurology · 2026Article
- The effect of physical exercise on the spiritual well-being of older adults-mediating role of self-care ability.PloS one · 2026Article
- Augmented Feedback in Post-Stroke Gait Rehabilitation Derived from Sensor-Based Gait Reports-A Longitudinal Case Series.Sensors (Basel, Switzerland) · 2025Article
- Pathophysiology and Management Strategies for Post-Stroke Spasticity: An Update Review.International journal of molecular sciences · 2025Review
- Observational
- LOWER-EXTREMITY CONSTRAINT-INDUCED MOVEMENT THERAPY IN INDIVIDUALS WITH STROKE - IMPROVEMENTS, EXPERIENCES AND HEALTH-RELATED QUALITY OF LIFE.Journal of rehabilitation medicine. Clinical communications · 2025Article
- Positive effects of lower extremity constraint-induced movement therapy on balance, leg strength and dual-task ability in stroke patients: a longitudinal cohort study.Journal of rehabilitation medicine · 2024Article
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo regain the ability to walk is one of the most commonly stated goals for people who have had a stroke due to its importance in everyday life. Walking ability affects patients' mobility, self-care, and social lives. Constraint-induced movement therapy (CIMT) is known to be effective in improving upper extremity outcomes post-stroke. However, there is insufficient evidence regarding its efficacy in improving lower extremity outcomes.
aimTo investigate whether a highly intensive CIMT for lower extremity (LE-CIMT) function post-stroke can improve motor function, functional mobility, and walking ability. Furthermore, it also aimed to investigate whether age, gender, stroke type, more-affected side, or time after stroke onset affect the efficacy of LE-CIMT on walking ability outcomes.
designLongitudinal cohort study.
settingOutpatient clinic in Stockholm, Sweden. POPULATION: A total of 147 patients mean age 51 years (68% males; 57% right-sided hemiparesis), at the sub-acute or chronic phases post-stroke who had not previously undergone LE-CIMT.
methodsAll patients received LE-CIMT for 6 hours per day over 2 weeks. The Fugl-Meyer Assessment (FMA) of the lower extremity, Timed Up and Go (TUG) test, Ten-Meter Walk Test (10MWT), and six-Minute Walk Test (6MWT) were used to assess functional outcomes before and directly after the 2-week treatment was complete as well at 3-month post-intervention.
resultsCompared to baseline values, FMA (P<0.001), TUG (P<0.001), 10MWT (P<0.001) and 6MWT (P<0.001) scores were statistically significantly improved directly after the LE-CIMT intervention. These improvements persisted at the 3-month post-intervention follow-up. Those who completed the intervention 1-6 months after stroke onset had statistically significant larger improvements in 10MWT compared to those who received the intervention later than 6 months after stroke onset. Age, gender, stroke type, and more-affected side did not impact 10MWT results.
conclusionsIn an outpatient clinic setting, high-intensity LE-CIMT statistically significant improved motor function, functional mobility, and walking ability in middle-aged patients in the sub-acute and chronic post-stroke phases. However, studies with more robust designs need to be conducted to deepen the understanding of the efficacy of LE-CIMT. CLINICAL REHABILITATION IMPACT: High-intensity LE-CIMT may be a feasible and useful treatment option in outpatient clinics to improve post-stroke walking ability.
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Registered trials
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