ArticleJournal of the American Heart Association2023
Burden, Trends, and Inequalities of Heart Failure Globally, 1990 to 2019: A Secondary Analysis Based on the Global Burden of Disease 2019 Study.
Article in Journal of the American Heart Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 149 papers, 13 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
149 citing papers in PubMed, 13 syntheses or guidelines pooled it, 209 citations in OpenAlex.
- Patients' Experiences of Nurse-Led eHealth Interventions for Chronic Heart Failure: Qualitative Systematic Review and Meta-Synthesis.Journal of medical Internet research · 2026Pooled it
- Efficacy of plant extracts in heart failure patients: a systematic review and network meta-analysis.BMC cardiovascular disorders · 2026Pooled it
- Peak oxygen uptake in older adults with heart failure: a systematic review and meta-analysis.GeroScience · 2026Pooled it
- Dose‒response relationships of DASH, Mediterranean, and AHEI dietary patterns with heart failure incidence: a systematic review and meta-analysis of cohort studies.European journal of clinical nutrition · 2026Pooled it
- Sleep Disorder Phenotypes and the Risk of Incident Heart Failure:Saudi medical journal · 2026Pooled it
- Cardiopulmonary Remodeling In Nondiabetic Patients with Systolic Heart Failure Using Sodium-Glucose Cotransporter 2 Inhibitors: An Updated Systematic Review and Meta-Analysis of Randomized Clinical Trials.Current cardiology reviews · 2026Pooled it
- Depression and cardiovascular disease: mind the gap in the guidelines.European heart journal · 2025Pooled it
- Heart failure: assessment of the global economic burden.European heart journal · 2025Pooled it
- Assessing suicide risk in patients with heart failure: a systematic review and meta-analysis.Frontiers in psychiatry · 2025Pooled it
- Acetazolamide therapy in patients with acute heart failure: a systematic review and meta-analysis of randomized controlled trials.Heart failure reviews · 2024Pooled it
- Effects of different sodium-glucose cotransporter 2 inhibitors in heart failure with reduced or preserved ejection fraction: a network meta-analysis.Frontiers in cardiovascular medicine · 2024Pooled it
- Spirituality and heart failure: a systematic review.Aging clinical and experimental research · 2023Pooled it
- Pooled it
- Impact of Simultaneous Initiation of Finerenone and Empagliflozin on Albuminuria Irrespective of Baseline HbA1c Levels: A Participant-Level Exploratory Analysis of the Randomised CONFIDENCE Trial.Diabetes, obesity & metabolism · 2026Trial
- The Effect of Vericiguat on Endothelial Function in Patients With Heart Failure With Reduced Ejection Fraction: A Pilot Randomized Study.The American journal of cardiology · 2026Trial
- Conduction System Pacing vs Biventricular Pacing in Chronic Heart Failure: Protocol for the Economic Analysis of the PhysioSync-HF Trial.Arquivos brasileiros de cardiologia · 2025Trial
- Molecular Mechanisms Governing Vascular Function in Heart Failure.Arteriosclerosis, thrombosis, and vascular biology · 2026Review
- Cardiac, oxidative stress, and fibrosis-related biomarkers and new-onset heart failure: Systematic review and meta-analysis.International journal of cardiology. Cardiovascular risk and prevention · 2026Article
- Heart Failure in Focus: Acute Presentation, Risk Factors and Integration of Artificial Intelligence.Journal of cardiovascular development and disease · 2026Article
- Health-Related Quality of Life and Associated Factors in Patients with Heart Failure Across Three Ejection Fraction Categories: A Two-Center Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2026Article
89 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background Heart failure is a public health issue worldwide. However, no comprehensive study on the global burden of heart failure and its contributing causes has been reported. The present study aimed to quantify the burden, trends, and inequalities of heart failure globally. Methods and Results Heart failure data were extracted from the Global Burden of Diseases 2019 study. The number of cases, age-standardized prevalence, and years lived with disability in different locations from 1990 to 2019 were presented and compared. Joinpoint regression analysis was performed to assess trends in heart failure from 1990 to 2019. In 2019, the global age-standardized prevalence and years lived with disability rates for heart failure were 711.90 (95% uncertainty interval [UI], 591.15-858.29) and 63.92 (95% UI, 41.49-91.95) per 100 000 population, respectively. In general, the age-standardized rate decreased globally at an average annual percentage change of 0.3% (95% UI, 0.2-0.3). However, the rate increased at an average annual percentage change of 0.6% (95% UI, 0.4-0.8) from 2017 to 2019. Several nations and territories demonstrated an increased trend from 1990 to 2019, especially in less-developed countries. Ischemic heart disease and hypertensive heart disease accounted for the highest proportion of heart failure in 2019. Conclusions Heart failure remains a major health problem, with increased trends possible in the future. Efforts for prevention and control of heart failure should focus more on less-developed regions. It is essential to prevent and treat primary diseases such as ischemic heart disease and hypertensive heart disease for the control of heart failure.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.