Evidence map›Paper›PMID 36892085›Full record

ArticleJournal of the American Heart Association2023

QRS Fragmentation in Preserved Ejection Fraction Heart Failure: Functional Insights, Pathological Correlates, and Prognosis.

Kuo-Tzu Sung, Sheng-Hsiung Chang, Po-Ching Chi, Shih-Chieh Chien, Chi-In Lo, Chao-Feng Lin, Wen-Hung Huang, Chun-Ho Yun, Cheng-Ting Tsai, Cheng-Huang Su and 5 more

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Electrocardiographic characteristics of bladder cancer patients receiving preoperative chemotherapy combined with immunotherapy.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Kuo-Tzu SungDepartment of Internal Medicine, Cardiovascular Center and Division of Cardiology MacKay Memorial Hospital Taipei Taiwan (R.O.C).
Sheng-Hsiung ChangDepartment of Internal Medicine, Cardiovascular Center and Division of Cardiology MacKay Memorial Hospital Taipei Taiwan (R.O.C).
Po-Ching ChiDepartment of Cardiology Zhongmei Hospital Taoyuan Taiwan (R.O.C.).
Shih-Chieh ChienDepartment of Internal Medicine, Cardiovascular Center and Division of Cardiology MacKay Memorial Hospital Taipei Taiwan (R.O.C).
Chi-In LoDepartment of Internal Medicine, Cardiovascular Center and Division of Cardiology MacKay Memorial Hospital Taipei Taiwan (R.O.C).
Chao-Feng LinDepartment of Internal Medicine, Cardiovascular Center and Division of Cardiology MacKay Memorial Hospital Taipei Taiwan (R.O.C).
Wen-Hung HuangDepartment of Internal Medicine, Cardiovascular Center and Division of Cardiology MacKay Memorial Hospital Taipei Taiwan (R.O.C).
Chun-Ho YunDivision of Radiology MacKay Memorial Hospital Taipei Taiwan (R.O.C.).ORCID 0000-0002-2463-1726
Cheng-Ting TsaiDepartment of Internal Medicine, Cardiovascular Center and Division of Cardiology MacKay Memorial Hospital Taipei Taiwan (R.O.C).ORCID 0000-0001-7958-1394
Cheng-Huang SuDepartment of Internal Medicine, Cardiovascular Center and Division of Cardiology MacKay Memorial Hospital Taipei Taiwan (R.O.C).
Charles Jia-Yin HouDepartment of Internal Medicine, Cardiovascular Center and Division of Cardiology MacKay Memorial Hospital Taipei Taiwan (R.O.C).ORCID 0000-0001-6602-5532
Hung-I YehDepartment of Internal Medicine, Cardiovascular Center and Division of Cardiology MacKay Memorial Hospital Taipei Taiwan (R.O.C).ORCID 0000-0003-3206-0908
Chin-Ho TsaoMacKay Medical College New Taipei City Taiwan (R.O.C.).
Jen-Yuan KuoDepartment of Internal Medicine, Cardiovascular Center and Division of Cardiology MacKay Memorial Hospital Taipei Taiwan (R.O.C).ORCID 0000-0002-7082-932X
Chung-Lieh HungDepartment of Internal Medicine, Cardiovascular Center and Division of Cardiology MacKay Memorial Hospital Taipei Taiwan (R.O.C).ORCID 0000-0002-2858-3493

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Fragmented QRS (fQRS) morphology as a surrogate marker of the possible presence of myocardial scarring has been shown to confer a higher risk in patients with reduced ejection fraction heart failure. We aimed to investigate the pathophysiological correlates and prognostic implications of fQRS in patients with heart failure with preserved ejection fraction (HFpEF). Methods and Results We consecutively studied 960 patients with HFpEF (76.4±12.7 years, men: 37.2%). fQRS was assessed using a body surface ECG during hospitalization. QRS morphology was available and classified into 3 categories among 960 subjects with HFpEF as non-fQRS, inferior fQRS, and anterior/lateral fQRS groups. Despite comparable clinical features in most baseline demographics among the 3 fQRS categories, anterior/lateral fQRS showed significantly higher B-type natriuretic peptide/troponin levels (both

Indexed as

Heart FailureHeart Failure, DiastolicHeart Failure, SystolicElectrocardiographyHumansMalePrognosisStroke Volumefragmented QRS complexheart failure with preserved ejection fractionmortalityQRS duration

Identifiers

PMID36892085
PMCPMC10111515

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.