Evidence map›Paper›PMID 36891946›Full record

ArticleJournal of diabetes2023

U-shaped association between serum IGF2BP3 and T2DM: A cross-sectional study in Chinese population.

Xiaoying Wu, Wei Wang, Shujin Fan, Lili You, Feng Li, Xiaoyun Zhang, Hongshi Wu, Juying Tang, Yiqin Qi, Wanting Feng and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of diabetes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. mInternational journal of molecular medicine · 2026
    Review
  3. Mechanisms of gypenosides in type 2 diabetes mellitus via regulation of m6A methylase METTL3/14 and demethylase FTO.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025
    Article
  4. Article
  5. Article
  6. Review
  7. The latest progression of N6-methyladenosine (mFrontiers in endocrinology · 2025
    Review
  8. Downregulation ofJournal of clinical medicine research · 2024
    Article
  9. Article
  10. Article
  11. Heliyon · 2024
    Review
  12. Article
  13. Review
  14. The role of mFrontiers in endocrinology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Xiaoying WuDepartment of Endocrinology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China.
Wei WangDepartment of Endocrinology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China.
Shujin FanDepartment of Endocrinology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China.
Lili YouDepartment of Endocrinology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China.
Feng LiDepartment of Endocrinology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China.
Xiaoyun ZhangDepartment of Endocrinology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China.
Hongshi WuDepartment of Endocrinology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China.
Juying TangDepartment of Endocrinology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China.
Yiqin QiDepartment of Endocrinology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China.
Wanting FengDepartment of Endocrinology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China.
Li YanDepartment of Endocrinology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China.
Meng RenDepartment of Endocrinology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China.ORCID https://orcid.org/0000-0001-9935-1449
Sun Yat-sen University · CN

Funding

Guangdong Clinical Research Center for Metabolic Diseases 2020B1111170009National Natural Science Foundation of China 81900752National Natural Science Foundation of China U20A20352Natural Science Foundation of Guangdong Province 2019A1515011199
6 · The paper itself

Abstract

objectiveTo clarify the expression of N6-methyladenosine (m

methodsThe gene expression data set GSE25724 was obtained from the Gene Expression Omnibus, and a cluster heatmap was generated by using the R package ComplexHeatmap. Differential expression analysis for 13 m

resultsTwo upregulated (IGF2BP2 and IGF2BP3) and 5 downregulated (methyltransferase-like 3 [METTL3], alkylation repair homolog protein 1 [ALKBH1], YTH domain family 2 [YTHDF2], YTHDF3, and heterogeneous nuclear ribonucleoprotein [HNRNPC]) m

conclusionSeven significantly altered m

Indexed as

Diabetes Mellitus, Type 2RNA-Binding ProteinsAdultAlkB Homolog 1, Histone H2a DioxygenaseCross-Sectional StudiesEast Asian PeopleHumansMethyltransferasesRisk FactorsALKBH1 protein, humanAlkB Homolog 1, Histone H2a DioxygenaseIGF2BP2 protein, humanIGF2BP3 protein, humanMethyltransferasesMETTL3 protein, humanRNA-Binding Proteins2型糖尿病gene expression omnibusinsulin-like growth factor 2 mRNA-binding protein (IGF2BP)3N6-methyladenosine (m6A) RNA methylationN6 -甲基腺苷(m6A)RNA甲基化type 2 diabetes mellitus基因表达数据库胰岛素样生长因子2 mRNA结合蛋白3 (IGF2BP3)

Identifiers

PMID36891946
PMCPMC10101838
OpenAlexW4323652906

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.