SynthesisEndocrinology and metabolism (Seoul, Korea)2023
A Comprehensive Assessment of the Harms of Fine-Needle Aspiration Biopsy for Thyroid Nodules: A Systematic Review.
Synthesis in Endocrinology and metabolism (Seoul, Korea), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
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Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Korean Thyroid Association Guidelines on the Management of Differentiated Thyroid Cancers, Part II: Follow-up Surveillance after Initial Treatment 2026.Endocrinology and metabolism (Seoul, Korea) · 2026Guideline
- A Narrative Review of the 2023 Korean Thyroid Association Management Guideline for Patients with Thyroid Nodules.Endocrinology and metabolism (Seoul, Korea) · 2024Guideline
- Application of Liquid-Based Cytology Using the ThinPrep System to Thyroid Fine-Needle Aspiration Samples.Current protocols · 2026Article
- Pediatric lingual ectopic thyroid: two contrasting cases and a narrative literature review.Frontiers in pediatrics · 2026Article
- Risk-adapted trajectory selection for ultrasound-guided thyroid fine-needle aspiration biopsy: a multicenter study of in-plane and out-of-plane approaches.Frontiers in endocrinology · 2026Article
- Resolution-Adaptive Binning Enhances Machine Learning Modeling by Interbatch and Multiplatform Orbitrap-Based Shotgun Mass Spectrometry Data Integration.Analytical chemistry · 2025Article
- Evaluating Liquid Biopsy for Circulating Tumor DNA (ctDNA) Detection as a Complementary Diagnostic Tool in Thyroid Cancer Among Ecuadorian Women.International journal of molecular sciences · 2025Article
- Needle aspiration technique as a supportive tool for clinical diagnosis of anorectal atresia in calves.BMC veterinary research · 2025Article
- Thyroid function test profile in patients who have thyroid nodule and its correlation with ultrasound TIRAD scoring system and cytological results.Scientific reports · 2025Article
- Diagnostic Value of Fine Needle Aspiration in Diagnosis of Thyroid Nodules at the Endocrine Clinic of Hamadan City During a 10-Year Period, Iran.Journal of research in health sciences · 2025Article
- Assessing the feasibility of ChatGPT-4o and Claude 3-Opus in thyroid nodule classification based on ultrasound images.Endocrine · 2025Article
- Article
- Needle size for thyroid fine needle aspiration cytology. A single institution experience.Frontiers in surgery · 2024Article
- Thyroid Cancer Screening: How to Maximize Its Benefits and Minimize Its Harms.Endocrinology and metabolism (Seoul, Korea) · 2023Article
- To Screen or Not to Screen?Endocrinology and metabolism (Seoul, Korea) · 2023Article
- Life-Threatening Neck Hematoma After Fine-Needle Aspiration of a Thyroid Nodule in a Patient With End-Stage Renal Disease.AACE endocrinology and diabetesArticle
- Intrathyroidal Hematoma, Biphasic Thyroid Dysfunction, and Permanent Hypothyroidism After Fine Needle Aspiration Biopsy.AACE endocrinology and diabetesArticle
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgruoundThere have concerns related with the potential harms of fine-needle aspiration biopsy (FNAB). We aimed to summarize the clinical complications and evaluate the safety of FNAB.
methodsStudies related with the harms of FNAB were searched on MEDLINE, Embase, Cochrane library, and KoreaMed from 2012 to 2022. Also, studies reviewed in the previous systematic reviews were evaluated. Included clinical complications were postprocedural pain, bleeding events, neurological symptoms, tracheal puncture, infections, post-FNAB thyrotoxicosis, and needle tract implantation of thyroid cancers.
resultsTwenty-three cohort studies were included in this review. Nine studies which were related with FNAB-related pain showed that most of the subjects had no or mild discomfort. The 0% to 6.4% of the patients had hematoma or hemorrhage after FNAB, according to 15 studies. Vasovagal reaction, vocal cord palsy, and tracheal puncture have rarely described in the included studies. Needle tract implantation of thyroid malignancies was described in three studies reporting 0.02% to 0.19% of the incidence rate.
conclusionFNAB is considered to be a safe diagnostic procedure with rare complications, which are mainly minor events. Thorough assessement of the patients' medical condition when deciding to perform FNABs would be advisable to lower potential complications.
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