Evidence map›Paper›PMID 36891527›Full record

ArticleCardiovascular therapeutics2023

Mass Cytometry Reveals the Imbalanced Immune State in the Peripheral Blood of Patients with Essential Hypertension.

Rui Yang, Yuhong He, Honggang Zhang, Qiuju Zhang, Bingwei Li, Changming Xiong, Yubao Zou, Bingyang Liu

Open access · goldAbstract read
In one paragraph

Article in Cardiovascular therapeutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Rui YangInstitute of Microcirculation, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100005, China.ORCID https://orcid.org/0000-0002-9384-8398
Yuhong HeInstitute of Microcirculation, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100005, China.ORCID https://orcid.org/0000-0002-9311-5610
Honggang ZhangInstitute of Microcirculation, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100005, China.ORCID https://orcid.org/0000-0002-9567-1135
Qiuju ZhangInstitute of Microcirculation, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100005, China.ORCID https://orcid.org/0000-0002-3248-0278
Bingwei LiInstitute of Microcirculation, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100005, China.
Changming XiongState Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100037, China.
Yubao ZouState Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100037, China.
Bingyang LiuState Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100037, China.
Chinese Academy of Medical Sciences & Peking Union Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mounting evidence has confirmed that essential hypertension (EH) is closely related to low-grade inflammation, but there is still a lack of in-depth understanding of the state of immune cells in the circulating blood of patients with EH. We analyzed whether hypertensive peripheral blood immune cell balance was destroyed. The peripheral blood mononuclear cells (PBMCs) of all subjects were analyzed using time-of-flight cytometry (CyTOF) based on 42 kinds of metal-binding antibodies. CD45

Indexed as

CD4-Positive T-LymphocytesLeukocytes, MononuclearEssential HypertensionFlow CytometryHumansMonocytes

Identifiers

PMID36891527
PMCPMC9988372
OpenAlexW4322488279

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.