Evidence map›Paper›PMID 36891460›Full record

ReviewFrontiers in neuroscience2023

Three-photon excited fluorescence imaging in neuroscience: From principles to applications.

Yujie Xiao, Peng Deng, Yaoguang Zhao, Shasha Yang, Bo Li

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
10.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 28 citations in OpenAlex.

  1. Preclinical in-vivo cerebrovascular imaging in rodent models: Methods and applications in Alzheimer's disease.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Yujie XiaoState Key Laboratory of Medical Neurobiology, Department of Neurology, Ministry of Education (MOE), Frontiers Center for Brain Science, Institute for Translational Brain Research, Huashan Hospital, Fudan University, Shanghai, China.
Peng DengState Key Laboratory of Medical Neurobiology, Department of Neurology, Ministry of Education (MOE), Frontiers Center for Brain Science, Institute for Translational Brain Research, Huashan Hospital, Fudan University, Shanghai, China.
Yaoguang ZhaoState Key Laboratory of Medical Neurobiology, Department of Neurology, Ministry of Education (MOE), Frontiers Center for Brain Science, Institute for Translational Brain Research, Huashan Hospital, Fudan University, Shanghai, China.
Shasha YangState Key Laboratory of Medical Neurobiology, Department of Neurology, Ministry of Education (MOE), Frontiers Center for Brain Science, Institute for Translational Brain Research, Huashan Hospital, Fudan University, Shanghai, China.
Bo LiState Key Laboratory of Medical Neurobiology, Department of Neurology, Ministry of Education (MOE), Frontiers Center for Brain Science, Institute for Translational Brain Research, Huashan Hospital, Fudan University, Shanghai, China.
Huashan Hospital · CNFudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The development of three-photon microscopy (3PM) has greatly expanded the capability of imaging deep within biological tissues, enabling neuroscientists to visualize the structure and activity of neuronal populations with greater depth than two-photon imaging. In this review, we outline the history and physical principles of 3PM technology. We cover the current techniques for improving the performance of 3PM. Furthermore, we summarize the imaging applications of 3PM for various brain regions and species. Finally, we discuss the future of 3PM applications for neuroscience.

Indexed as

deep brain imagingfunctional imagingrodentsstructural imagingthree-photon excited fluorescence microscopy

Identifiers

PMID36891460
PMCPMC9986337
OpenAlexW4321377026

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.