Evidence map›Paper›PMID 36891302›Full record

ArticleFrontiers in immunology2023

Identification of a DRB3*011:01-restricted CD4

Bryan S Kaplan, Amelia R Hofstetter, Jodi L McGill, John D Lippolis, Junzo Norimine, Rohana P Dassanayake, Randy E Sacco

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Bryan S KaplanRuminant Diseases & Immunology Research Unit, National Animal Disease Center, Agricultural Research Service, United States Department of Agriculture, Ames, IA, United States.
Amelia R HofstetterRuminant Diseases & Immunology Research Unit, National Animal Disease Center, Agricultural Research Service, United States Department of Agriculture, Ames, IA, United States.
Jodi L McGillDepartment of Veterinary Microbiology and Preventive Medicine, Iowa State University, Ames, IA, United States.
John D LippolisRuminant Diseases & Immunology Research Unit, National Animal Disease Center, Agricultural Research Service, United States Department of Agriculture, Ames, IA, United States.
Junzo NorimineDepartment of Veterinary Medicine, University of Miyazaki, Miyazaki, Japan.
Rohana P DassanayakeRuminant Diseases & Immunology Research Unit, National Animal Disease Center, Agricultural Research Service, United States Department of Agriculture, Ames, IA, United States.
Randy E SaccoRuminant Diseases & Immunology Research Unit, National Animal Disease Center, Agricultural Research Service, United States Department of Agriculture, Ames, IA, United States.
Agricultural Research Service · USIowa State University · USNational Animal Disease Center · USUnited States Department of Agriculture · USUniversity of Miyazaki · JP

Funding

Development of a mucosal, polyanhydride-based nanoparticle vaccine for use against RSV infection in the neonateR01HD095880 · NICHD · IOWA STATE UNIVERSITY · PI MCGILL, JODI, SACCO, RANDY E · 2019 to 2022
$2.1M
NICHD NIH HHS R01 HD095880
6 · The paper itself

Abstract

Although Human Respiratory Syncytial Virus (HRSV) is a significant cause of severe respiratory disease with high morbidity and mortality in pediatric and elderly populations worldwide there is no licensed vaccine. Bovine Respiratory Syncytial Virus (BRSV) is a closely related orthopneumovirus with similar genome structure and high homology between structural and nonstructural proteins. Like HRSV in children, BRSV is highly prevalent in dairy and beef calves and known to be involved in the etiology of bovine respiratory disease, in addition to being considered an excellent model for HRSV. Commercial vaccines are currently available for BRSV, though improvements in efficacy are needed. The aims of this study were to identify CD4

Indexed as

Respiratory Syncytial Virus, BovineRespiratory Syncytial Virus, HumanRespiratory Syncytial Virus InfectionsAgedAnimalsCattleCD4-Positive T-LymphocytesChildEpitopes, T-LymphocyteHumansT-LymphocytesEpitopes, T-Lymphocyteantigen presentationBoLA class IIBRSVcattleF proteinT cell

Identifiers

PMID36891302
PMCPMC9986546
OpenAlexW4321375721

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.