Evidence map›Paper›PMID 36891056›Full record

ReviewFrontiers in endocrinology2023

Endometriosis and dysbiosis: State of art.

Brunella Zizolfi, Virginia Foreste, Alessandra Gallo, Simona Martone, Peirluigi Giampaolino, Attilio Di Spiezio Sardo

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in endocrinology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
7.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.

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  9. The Role of the Microbiome in Endometriosis.Reproductive sciences (Thousand Oaks, Calif.) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Brunella ZizolfiDepartment of Public Health, University of Naples Federico II, Naples, Italy.
Virginia ForesteDepartment of Public Health, University of Naples Federico II, Naples, Italy.
Alessandra GalloDepartment of Public Health, University of Naples Federico II, Naples, Italy.
Simona MartoneDepartment of Molecular and Developmental Medicine, University of Siena, Siena, Italy.
Peirluigi GiampaolinoDepartment of Public Health, University of Naples Federico II, Naples, Italy.
Attilio Di Spiezio SardoDepartment of Public Health, University of Naples Federico II, Naples, Italy.
University of Naples Federico II · ITUniversity of Siena · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endometriosis is a complex and heterogeneous disease affecting approximately 10% of reproductive age women. The hypothesis that alterations in the microbiota are involved in the pathogenesis of endometriosis has been postulated. Possible explanations for the implications of dysbiosis in endometriosis include the Bacterial Contamination hypothesis and immune activation, cytokine-impaired gut function, altered estrogen metabolism and signaling. Thus, dysbiosis, disrupt normal immune function, leading to the elevation of proinflammatory cytokines, compromised immunosurveillance and altered immune cell profiles, all of which may contribute to the pathogenesis of endometriosis. The aim of this review is to summarize the available literature data about the relationship between microbiota and endometriosis.

Indexed as

EndometriosisGastrointestinal MicrobiomeMicrobiotaDysbiosisFemaleHumansReproductiondysbiosisendometriosisestrobolomeinfertilitymicrobiota

Identifiers

PMID36891056
PMCPMC9986482
OpenAlexW4321375859

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.