Evidence map›Paper›PMID 36890909›Full record

ArticleFrontiers in bioengineering and biotechnology2023

Synthetic peptides for the precise transportation of proteins of interests to selectable subcellular areas.

Junyi Song, Chuanyang Liu, Baoshan Li, Liangcheng Liu, Ling Zeng, Zonghuang Ye, Wenjian Wu, Lingyun Zhu, Biru Hu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Junyi SongDepartment of Biology and Chemistry, College of Science, National University of Defense Technology, Changsha, Hunan, China.
Chuanyang LiuDepartment of Biology and Chemistry, College of Science, National University of Defense Technology, Changsha, Hunan, China.
Baoshan LiDepartment of Biology and Chemistry, College of Science, National University of Defense Technology, Changsha, Hunan, China.
Liangcheng LiuDepartment of Biology and Chemistry, College of Science, National University of Defense Technology, Changsha, Hunan, China.
Ling ZengDepartment of Biology and Chemistry, College of Science, National University of Defense Technology, Changsha, Hunan, China.
Zonghuang YeDepartment of Biology and Chemistry, College of Science, National University of Defense Technology, Changsha, Hunan, China.
Wenjian WuDepartment of Biology and Chemistry, College of Science, National University of Defense Technology, Changsha, Hunan, China.
Lingyun ZhuDepartment of Biology and Chemistry, College of Science, National University of Defense Technology, Changsha, Hunan, China.
Biru HuDepartment of Biology and Chemistry, College of Science, National University of Defense Technology, Changsha, Hunan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Proteins, as gifts from nature, provide structure, sequence, and function templates for designing biomaterials. As first reported here, one group of proteins called reflectins and derived peptides were found to present distinct intracellular distribution preferences. Taking their conserved motifs and flexible linkers as Lego bricks, a series of reflectin-derivates were designed and expressed in cells. The selective intracellular localization property leaned on an RMs (canonical conserved reflectin motifs)-replication-determined manner, suggesting that these linkers and motifs were constructional fragments and ready-to-use building blocks for synthetic design and construction. A precise spatiotemporal application demo was constructed in the work by integrating RL

Indexed as

cyto/nucleoplasmic locationpreselected and spatiotemporal tunableprotein transportationRfA1synthetic peptide

Identifiers

PMID36890909
PMCPMC9986269

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.