Evidence map›Paper›PMID 36890529›Full record

Trial reportBMC oral health2023

Does intra-articular injection of tenoxicam after arthrocentesis heal outcomes of temporomandibular joint osteoarthritis? A randomized clinical trial.

Zeynep Bayramoglu, Günay Yapici Yavuz, Aydın Keskinruzgar, Mahmut Koparal, Göksel Simsek Kaya

2 registry-linked trialsOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC oral health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 15 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 6 pooled it
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05497570 phase1completednot on this map

Does Intra-articular Injection of Tenoxicam After Arthrocentesis Heal Outcomes of Temporomandibular Joint Osteoarthritis? A Randomized Clinical Trial

TypeinterventionalSponsorAtaturk UniversityRan2019 to 2022Enrolled30ConditionsArthrocentesisArmsTenoxicam Injectable Product
NCT06572904 phase1 / phase2active not recruitingnot on this mapstarted 2024, after this paper: background citation

Effect of Intraarticular Injection of Tenoxicam and Hyaluronic Acid Versus Platelet-Rich Plasma and Hyaluronic Acid in Temporomandibular Joint Internal Derangement

TypeinterventionalSponsorMansoura UniversityRan2024 to 2024Enrolled60ConditionsTemporomandibular Joint Internal DerangementArmsTenoxicam Injectable Product, Hyaluronic Acid 20 MG/1 ML Injection Gel/Jelly
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 6 syntheses or guidelines pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Trial
  8. Review
  9. Review
  10. Review
  11. Review
  12. Review
  13. Review
  14. Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Zeynep BayramogluDepartment of Oral, Dental and Maxillofacial Surgery, Ataturk University, Erzurum, Turkey. zeynep0569@hotmail.com.ORCID 0000-0002-3238-8084
Günay Yapici YavuzDepartment of Oral, Dental and Maxillofacial Surgery, Faculty of Dentistry, Adıyaman University, Adıyaman, Turkey.ORCID 0000-0002-1093-6297
Aydın KeskinruzgarDepartment of Oral, Dental and Maxillofacial Surgery, Faculty of Dentistry, Adıyaman University, Adıyaman, Turkey.ORCID 0000-0001-5735-6890
Mahmut KoparalDepartment of Oral, Dental and Maxillofacial Surgery, Faculty of Dentistry, Adıyaman University, Adıyaman, Turkey.ORCID 0000-0003-1817-1230
Göksel Simsek KayaDepartment of Oral, Dental and Maxillofacial Surgery, Faculty of Dentistry, Akdeniz University, Antalya, Turkey.ORCID 0000-0003-3398-5574
Adıyaman University · TRAkdeniz University · TRAtatürk University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTemporomandibular joint osteoarthritis (TMJ-OA) is a degenerative disease and manifests itself with pain and limitation of movement in the jaws. Arthrocentesis alone or in combination with intraarticular injections is one of the most commonly used treatment methods in these patients. The aim of the study is to examine the effectiveness of arthrocentesis plus tenoxicam injection and to compare it with arthrocentesis alone in patients with TMJ-OA.

methodsThirty patients with TMJ-OA who were treated randomly with either arthrocentesis plus tenoxicam injection (TX group) or arthrocentesis alone (control group) were examined. Maximum mouth opening (MMO), visual analog scale (VAS) pain values, and joint sounds were the outcome variables, which were evaluated at pre-treatment and at 1, 4, 12, and 24 weeks after treatment. Statistical significance was set at p < 0.05.

resultsThe gender distribution and mean age were not significantly different between the two groups. Pain values (p < 0.001), MMO (p < 0.001), and joint sounds (p < 0.001) improved significantly in both groups. However, there was no significant difference between the groups in terms of outcome variables [pain (p = 0.085), MMO (p = 0.174), joint sounds (p = 0.131)].

conclusionsArthrocentesis plus tenoxicam injection showed no better outcomes in terms of MMO, pain, and joint sounds compared with arthrocentesis alone in patients with TMJ-OA.

trial registrationInjection of Tenoxicam Versus Arthrocentesis Alone in the Treatment of Temporomandibular Joint Osteoarthritis, NCT05497570. Registered 11 May 2022. Retrospectively registered, https://register. CLINICALTRIALS: gov/prs/app/action/SelectProtocol?sid=S000CD7A&selectaction=Edit&uid=U0006FC4&ts=6&cx=f3anuq.

Indexed as

OsteoarthritisTemporomandibular Joint DisordersArthrocentesisHumansHyaluronic AcidInjections, Intra-ArticularPainPiroxicamRange of Motion, ArticularTemporomandibular JointTreatment OutcomeHyaluronic AcidPiroxicamtenoxicamArthrocentesisIntra-articular injectionTemporomandibular joint osteoarthritisTenoxicam

Identifiers

PMID36890529
PMCPMC9996841
OpenAlexW4323543874

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.