Evidence map›Paper›PMID 36890512›Full record

Trial reportBMC health services research2023

Effectiveness of digital care platform CMyLife for patients with chronic myeloid leukemia: results of a patient-preference trial.

Lynn Verweij, Geneviève I C G Ector, Yolba Smit, Bas van Vlijmen, Bert A van der Reijden, Rosella P M G Hermens, Nicole M A Blijlevens

Registry-linked trialAbstract readClinical Trial
In one paragraph

Trial report in BMC health services research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04595955 (Effectiveness of the Digital Patient Platform CMyLife for Patients With Chronic Myeloid Leukemia), which is not on this map. Cited by 11 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04595955 nacompletednot on this map

Effectiveness of the Digital Patient Platform CMyLife for Patients With Chronic Myeloid Leukemia

TypeinterventionalSponsorRadboud University Medical CenterRan2019 to 2020Enrolled99ConditionsNeoplasms, Chronic Myeloid Leukemia, Patient Portals, TelemedicineArmsCMyLife
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Feasibility and preliminary effects of mhealth supportive care interventions in adults with myeloid neoplasms: a systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lynn VerweijDepartment of Hematology, Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, Netherlands. lynn.verweij@radboudumc.nl.ORCID http://orcid.org/0000-0003-3904-9509
Geneviève I C G EctorDepartment of Hematology, Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, Netherlands.ORCID https://orcid.org/0000-0002-1558-944X
Yolba SmitDepartment of Hematology, Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, Netherlands.ORCID https://orcid.org/0000-0003-4799-4981
Bas van VlijmenDepartment of Pharmacy, Radboud University Medical Center, Nijmegen, Netherlands.ORCID https://orcid.org/0000-0003-4387-2119
Bert A van der ReijdenDepartment of Laboratory Medicine, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, Netherlands.ORCID https://orcid.org/0000-0001-7804-8643
Rosella P M G Hermens *Department of IQ Healthcare, Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, Netherlands.ORCID https://orcid.org/0000-0001-7624-7120
Nicole M A Blijlevens *Department of Hematology, Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, Netherlands.ORCID https://orcid.org/0000-0002-1801-2072

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTwo most important factors determining treatment success in chronic myeloid leukemia (CML) are adequate medication compliance and molecular monitoring albeit still being suboptimal. The CMyLife platform is an eHealth innovation, co-created with and for CML patients, aiming to improve their care, leading to an increased quality of life and the opportunity of hospital-free care.

objectiveTo explore the effectiveness of CMyLife in terms of information provision, patient empowerment, medication compliance, molecular monitoring, and quality of life.

methodsEffectiveness of CMyLife was explored using a patient-preference trial. Upon completion of the baseline questionnaire, participants actively used (intervention group) or did not actively use (questionnaire group) the CMyLife platform for at least 6 months, after which they completed the post-intervention questionnaire. Scores between the intervention group and the questionnaire group were compared with regard to the within-subject change between baseline and post-measurement using Generalized Estimating Equation models.

resultsAt baseline, 33 patients were enrolled in the questionnaire group and 75 in the intervention group. Online health information knowledge improved significantly when actively using CMyLife and patients felt more empowered. No significant improvements were found regarding medication compliance and molecular monitoring, which were already outstanding. Self-reported effectiveness showed that patients experienced that using CMyLife improved their medication compliance and helped them to oversee their molecular monitoring. Patients using CMyLife reported more symptoms but were better able to manage these.

conclusionsSince hospital-free care has shown to be feasible in time of the COVID-19 pandemic, eHealth-based innovations such as CMyLife could be a solution to maintain the quality of care and make current oncological health care services more sustainable.

trial registrationClinicalTrials.gov NCT04595955 , 22/10/2020.

Indexed as

COVID-19Leukemia, Myelogenous, Chronic, BCR-ABL PositiveChronic DiseaseHumansPandemicsQuality of LifeCMLDigital care platformGuideline adherenceInformation provisionMedication complianceMolecular monitoringPatient empowermentQuality of life

Identifiers

PMID36890512
PMCPMC9994406

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.