Evidence map›Paper›PMID 36890487›Full record

ReviewBMC pregnancy and childbirth2023

Spontaneous skull base cerebrospinal fluid leak during pregnancy: a case report and review of the literature.

Lauren Michelle, Rebecca J Post, Edward C Kuan, Michael P Nageotte

Open access · goldAbstract readReviewCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Review in BMC pregnancy and childbirth, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Lauren MichelleDepartment of Otolaryngology - Head and Neck Surgery, University of California Irvine Medical Center, Orange, CA, USA.
Rebecca J PostDepartment of Obstetrics and Gynecology, University of California Irvine Medical Center, 3800 West Chapman Ave, Ste 3800, Orange, CA, USA. rpost@uci.edu.ORCID http://orcid.org/0000-0001-5652-5816
Edward C KuanDepartment of Otolaryngology - Head and Neck Surgery, University of California Irvine Medical Center, Orange, CA, USA.
Michael P NageotteDepartment of Obstetrics and Gynecology, University of California Irvine Medical Center, 3800 West Chapman Ave, Ste 3800, Orange, CA, USA.
University of California, Irvine Medical Center · USChapman University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIdiopathic intracranial hypertension can lead to dural defects and spontaneous leakage of cerebrospinal fluid (CSF) from the skull base. Skull base CSF leaks are rarely reported in pregnancy but pose unique challenges for obstetricians and anesthesiologists. CASE PRESENTATION: A 31-year-old G4P1021 at 14 weeks developed debilitating headaches and CSF rhinorrhea. Brain imaging revealed a bony defect of the sphenoid sinus with a meningoencephalocele and a partially empty sella, consistent with CSF leakage from a skull base defect. The patient was neurologically stable without signs of meningitis; thus, management was focused on symptomatic alleviation. A planned cesarean section was performed at 38 weeks under spinal anesthesia. The patient had spontaneous marked improvement of her symptoms postpartum.

conclusionPregnancy may exacerbate skull base CSF leaks, requiring careful management with a multidisciplinary team. Neuraxial anesthesia can safely be performed in pregnant individuals with spontaneous skull base CSF leakage, but further studies are needed to determine the safest mode of delivery in these patients.

Indexed as

Cerebrospinal Fluid RhinorrheaIntracranial HypertensionAdultCerebrospinal Fluid LeakCesarean SectionFemaleHumansPregnancySkull BaseCase reportCerebrospinal fluid leakIdiopathic intracranial hypertensionNeuraxial anesthesiaPregnancyRhinorrhea

Identifiers

PMID36890487
PMCPMC9993356
OpenAlexW4323566074

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.