Evidence map›Paper›PMID 36890370›Full record

ArticleNature2023

Population-based heteropolymer design to mimic protein mixtures.

Zhiyuan Ruan, Shuni Li, Alexandra Grigoropoulos, Hossein Amiri, Shayna L Hilburg, Haotian Chen, Ivan Jayapurna, Tao Jiang, Zhaoyi Gu, Alfredo Alexander-Katz and 3 more

Erratum issuedAbstract read
In one paragraph

Article in Nature, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Tuning Polyacrylate Composition to Recognize and Modulate Fluorescent Proteins.Angewandte Chemie (International ed. in English) · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Sequence-Sensitivity in Functional Synthetic Polymer Properties.Angewandte Chemie (International ed. in English) · 2025
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Zhiyuan RuanDepartment of Materials Science and Engineering, University of California Berkeley, Berkeley, CA, USA.ORCID http://orcid.org/0000-0001-9083-7952
Shuni LiDepartment of Statistics, University of California Berkeley, Berkeley, CA, USA.
Alexandra GrigoropoulosDepartment of Materials Science and Engineering, University of California Berkeley, Berkeley, CA, USA.
Hossein AmiriInstitute for Quantitative Biosciences-QB3, University of California, Berkeley, CA, USA.ORCID http://orcid.org/0000-0003-2285-2805
Shayna L HilburgDepartment of Materials Science and Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.ORCID http://orcid.org/0000-0003-0825-7698
Haotian ChenDepartment of Materials Science and Engineering, University of California Berkeley, Berkeley, CA, USA.
Ivan JayapurnaDepartment of Materials Science and Engineering, University of California Berkeley, Berkeley, CA, USA.ORCID http://orcid.org/0000-0003-1070-1014
Tao JiangDepartment of Materials Science and Engineering, University of California Berkeley, Berkeley, CA, USA.ORCID http://orcid.org/0000-0003-3042-1247
Zhaoyi GuDepartment of Materials Science and Engineering, University of California Berkeley, Berkeley, CA, USA.
Alfredo Alexander-KatzDepartment of Materials Science and Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
Carlos BustamanteInstitute for Quantitative Biosciences-QB3, University of California, Berkeley, CA, USA.ORCID http://orcid.org/0000-0002-2970-0073
Haiyan HuangDepartment of Statistics, University of California Berkeley, Berkeley, CA, USA.
Ting XuDepartment of Materials Science and Engineering, University of California Berkeley, Berkeley, CA, USA. tingxu@berkeley.edu.ORCID http://orcid.org/0000-0002-2831-2095

Funding

Defense Threat Reduction Agency HDTRA1-19-1-0011National Science Foundation DMR-2104443US Department of Defense W911NF-13-1-0232US Department of Energy DE-AC02-05-CH11231US Department of Energy DE-AC02-06CH1135
6 · The paper itself

Abstract

Biological fluids, the most complex blends, have compositions that constantly vary and cannot be molecularly defined

Indexed as

Biomimetic MaterialsBiomimeticsPolymersProtein ConformationProtein FoldingProteinsAmino Acid SequenceBody FluidsCytosolSerum Albumin, BovineSynthetic BiologyPolymersProteinsSerum Albumin, Bovine

Identifiers

PMID36890370
PMCPMC10468399

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.