ArticleCognitive, affective & behavioral neuroscience2023
Age differences in the neural basis of decision-making under uncertainty.
Article in Cognitive, affective & behavioral neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Similarities and differences in the late-onset GM2 gangliosidoses: Tay-Sachs and Sandhoff diseases.Journal of neurology · 2026Article
- Large language models accurately identify decision reasons in verbal reports.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- A behavioural and neurobiological assessment of effort-based decision-making in cannabis use disorder: An initial/preliminary investigation.Cognitive, affective & behavioral neuroscience · 2025Article
- Unraveling Microstructural and Macrostructural Brain Age Dynamics in Multiple Sclerosis.Neurology(R) neuroimmunology & neuroinflammation · 2025Article
- Similarities and Differences in the Late-Onset GM2 Gangliosidoses: Tay-Sachs and Sandhoff Diseases.medRxiv : the preprint server for health sciences · 2025Article
- Deep Learning Cerebellar Magnetic Resonance Imaging Segmentation in Late-Onset GM2 Gangliosidosis: Implications for Phenotype.medRxiv : the preprint server for health sciences · 2025Article
- Association and benefits of 24-h activity behavior and academic procrastination among Chinese college students based on the isotemporal substitution model.Frontiers in public health · 2025Article
- Convergence of Age Differences in Risk Preference, Impulsivity, and Self-Control: A Multiverse Analysis.The journals of gerontology. Series B, Psychological sciences and social sciences · 2024Article
- A mediation approach in resting-state connectivity between the medial prefrontal cortex and anterior cingulate in mild cognitive impairment.Aging clinical and experimental research · 2024Article
- Influence of age and cognitive demand on motor decision making under uncertainty: a study on goal directed reaching movements.Scientific reports · 2024Article
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Authors and funding
2 authors.
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Abstract
Humans globally are reaping the benefits of longer lives. Yet, longer life spans also require engaging with consequential but often uncertain decisions well into old age. Previous research has yielded mixed findings with regards to life span differences in how individuals make decisions under uncertainty. One factor contributing to the heterogeneity of findings is the diversity of paradigms that cover different aspects of uncertainty and tap into different cognitive and affective mechanisms. In this study, 175 participants (53.14% females, mean age = 44.9 years, SD = 19.0, age range = 16 to 81) completed functional neuroimaging versions of two prominent paradigms in this area, the Balloon Analogue Risk Task and the Delay Discounting Task. Guided by neurobiological accounts of age-related changes in decision-making under uncertainty, we examined age effects on neural activation differences in decision-relevant brain structures, and compared these across multiple contrasts for the two paradigms using specification curve analysis. In line with theoretical predictions, we find age differences in nucleus accumbens, anterior insula, and medial prefrontal cortex, but the results vary across paradigm and contrasts. Our results are in line with existing theories of age differences in decision making and their neural substrates, yet also suggest the need for a broader research agenda that considers how both individual and task characteristics determine the way humans deal with uncertainty.
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