Evidence map›Paper›PMID 36890338›Full record

ArticleLifetime data analysis2023

Latency function estimation under the mixture cure model when the cure status is available.

Wende Clarence Safari, Ignacio López-de-Ullibarri, María Amalia Jácome

Abstract read
In one paragraph

Article in Lifetime data analysis, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Fitting high-dimensional mixture cure models using the hdcuremodelsR package.Computer methods and programs in biomedicine · 2026
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Wende Clarence SafariInequalities in Cancer Outcomes Network (ICON), Department of Non-Communicable Disease Epidemiology, Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK. wende.safari@lshtm.ac.uk.ORCID 0000-0003-4639-7552
Ignacio López-de-UllibarriDepartment of Mathematics, Escuela Universitaria Politécnica, University of A Coruña, Ferrol, Spain.
María Amalia JácomeDepartment of Mathematics, Faculty of Science, University of A Coruña, CITIC, A Coruña, Spain.

Funding

Cancer Research UK 29018
6 · The paper itself

Abstract

This paper addresses the problem of estimating the conditional survival function of the lifetime of the subjects experiencing the event (latency) in the mixture cure model when the cure status information is partially available. The approach of past work relies on the assumption that long-term survivors are unidentifiable because of right censoring. However, in some cases this assumption is invalid since some subjects are known to be cured, e.g., when a medical test ascertains that a disease has entirely disappeared after treatment. We propose a latency estimator that extends the nonparametric estimator studied in López-Cheda et al. (TEST 26(2):353-376, 2017b) to the case when the cure status is partially available. We establish the asymptotic normality distribution of the estimator, and illustrate its performance in a simulation study. Finally, the estimator is applied to a medical dataset to study the length of hospital stay of COVID-19 patients requiring intensive care.

Indexed as

COVID-19Models, StatisticalComputer SimulationHumansSurvival AnalysisBootstrap bandwidthCensoringCOVID-19Cure modelNadaraya-Watson weights

Identifiers

PMID36890338
PMCPMC9994787

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.