Evidence map›Paper›PMID 36889962›Full record

ArticleThe Journal of chemical physics2023

N-WASP is competent for downstream signaling before full release from autoinhibition.

Souvik Dey, Huan-Xiang Zhou

Abstract read
In one paragraph

Article in The Journal of chemical physics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Electrical Forces Improve Memory in Old Age.Reviews of physiology, biochemistry and pharmacology · 2025
    Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Souvik DeyDepartment of Chemistry, University of Illinois at Chicago, Chicago, Illinois 60607, USA.ORCID 0000-0002-4366-5681
Huan-Xiang ZhouDepartment of Chemistry, University of Illinois at Chicago, Chicago, Illinois 60607, USA.ORCID 0000-0001-9020-0302

Funding

Quantitative, Mechanistic Studies of Biomolecular RecognitionR35GM118091 · NIGMS · UNIVERSITY OF ILLINOIS AT CHICAGO · PI Huan-Xiang Zhou · 2016 to 2026
$6.5M
NIGMS NIH HHS R35 GM118091
6 · The paper itself

Abstract

Allosteric regulation of intrinsically disordered proteins (IDPs) is still vastly understudied compared to the counterpart of structured proteins. Here, we used molecular dynamics simulations to characterize the regulation of the IDP N-WASP by the binding of its basic region with inter- and intramolecular ligands (PIP

Indexed as

ActinsWiskott-Aldrich Syndrome ProteinProtein BindingSignal TransductionActinsWiskott-Aldrich Syndrome Protein

Identifiers

PMID36889962
PMCPMC9995167

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.