Evidence map›Paper›PMID 36889961›Full record

ArticleThe Journal of chemical physics2023

Determining the impact of gold nanoparticles on amyloid aggregation with 2D IR spectroscopy.

Kayla A Hess, Nathan J Spear, Sophia A Vogelsang, Janet E Macdonald, Lauren E Buchanan

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of chemical physics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Noble Metal Nanoparticles with Nanogel Coatings: Coinage Metal Thiolate-Stabilized Glutathione Hydrogel Shells.The journal of physical chemistry. C, Nanomaterials and interfaces · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Kayla A HessDepartment of Chemistry, Vanderbilt University, 1234 Stevenson Center Lane, Nashville, Tennessee 37235, USA.ORCID 0000-0002-6508-4423
Nathan J SpearDepartment of Chemistry, Vanderbilt University, 1234 Stevenson Center Lane, Nashville, Tennessee 37235, USA.ORCID 0000-0002-0881-6798
Sophia A VogelsangDepartment of Chemistry, Vanderbilt University, 1234 Stevenson Center Lane, Nashville, Tennessee 37235, USA.ORCID 0000-0002-5163-7613
Janet E MacdonaldDepartment of Chemistry, Vanderbilt University, 1234 Stevenson Center Lane, Nashville, Tennessee 37235, USA.ORCID 0000-0001-6256-0706
Lauren E BuchananDepartment of Chemistry, Vanderbilt University, 1234 Stevenson Center Lane, Nashville, Tennessee 37235, USA.ORCID 0000-0001-8486-0371
Vanderbilt University · US

Funding

MOLECULAR BIOPHYSICS TRAINING PROGRAM AT VANDERBILTT32GM008320 · NIGMS · VANDERBILT UNIVERSITY · PI CHAZIN, WALTER J. · 1989 to 2023
$7.9M
NIGMS NIH HHS T32 GM008320
6 · The paper itself

Abstract

As nanomaterials become more prevalent in both industry and medicine, it is crucial to fully understand their health risks. One area of concern is the interaction of nanoparticles with proteins, including their ability to modulate the uncontrolled aggregation of amyloid proteins associated with diseases, such as Alzheimer's disease and type II diabetes, and potentially extend the lifetime of cytotoxic soluble oligomers. This work demonstrates that two-dimensional infrared spectroscopy and

Indexed as

Diabetes Mellitus, Type 2Metal NanoparticlesAmyloidAmyloidogenic ProteinsGoldHumansIslet Amyloid PolypeptideSpectrophotometry, InfraredAmyloidAmyloidogenic ProteinsGoldIslet Amyloid Polypeptide

Identifiers

PMID36889961
PMCPMC9981241
OpenAlexW4322755619

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.