ArticleThe American journal of clinical nutrition2023
Total energy expenditure as assessed by doubly labeled water and all-cause mortality in a cohort of postmenopausal women.
Article in The American journal of clinical nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00000611 (Women's Health Initiative), which is not on this map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Women's Health Initiative (WHI)
Who cites it
6 citing papers in PubMed.
- Predictive equation derived from 6,497 doubly labelled water measurements enables the detection of erroneous self-reported energy intake.Nature food · 2025Article
- Diet and Chronic Disease Research in the Women's Health Initiative.Journal of the Academy of Nutrition and Dietetics · 2024Review
- Commentary on the Women's Health Initiative: Over 30 Years of Contribution to Nutrition and Dietetics.Journal of the Academy of Nutrition and Dietetics · 2024Article
- Intake Biomarkers for Nutrition and Health: Review and Discussion of Methodology Issues.Metabolites · 2024Review
- Biomarker-assessed total energy intake and its cohort study association with all-cause mortality in postmenopausal females.The American journal of clinical nutrition · 2024Article
- Association between doubly labelled water-calibrated energy intake and objectively measured physical activity with mortality risk in older adults.The international journal of behavioral nutrition and physical activity · 2023Article
Corrections and comments
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Authors and funding
12 authors.
Funding
Abstract
backgroundThe association of TEE with all-cause mortality is uncertain, as is the dependence of this association on age.
objectivesTo examine the association between TEE and all-cause mortality, and its age interaction, in a Women's Health Initiative (WHI) cohort of postmenopausal United States women (1992-present).
methodsA cohort of 1131 WHI participants having DLW TEE assessment of ∼10.0 y (median) following WHI enrollment with ∼13.7 y (median) of subsequent follow-up, was used to study the EE associations with all-cause mortality. To enhance the comparability of TEE and total EI, key analyses excluded participants having >5% weight change between WHI enrollment and DLW assessment. The influence of participant age on mortality associations was examined, as was the ability of concurrent and earlier weight and height measurements to explain the results.
resultsThere were 308 deaths following the TEE assessment through 2021. TEE was unrelated to overall mortality (P = 0.83) in this cohort of generally healthy, older (mean 71 y at TEE assessment) United States women. However, this potential association varied with age (P = 0.003). Higher TEE was associated with a higher mortality rate at the age of 60 y and a lower mortality rate at the age of 80 y. Within the weight-stable subset (532 participants, 129 deaths), TEE was weakly positively related to overall mortality (P = 0.08). This association also varied with age (P = 0.03), with mortality HRs (95% CIs) for a 20% increment in TEE of 2.33 (1.24, 4.36) at the age of 60 y, 1.49 (1.10, 2.02) at 70 y of age, and 0.96 (0.66, 1.38) at 80 y of age. This pattern remained, although was somewhat attenuated, following control for baseline weight and weight changes between WHI enrollment and TEE assessment.
conclusionsHigher EE is associated with higher all-cause mortality among younger postmenopausal women, only partially explained by weight and weight change. This study is registered with clinicaltrials.gov identifier: NCT00000611.
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