Evidence map›Paper›PMID 36889668›Full record

ArticleMicrovascular research2023

Activation of renal vascular smooth muscle TRPV4 channels by 5-hydroxytryptamine impairs kidney function in neonatal pigs.

Jeremiah M Afolabi, Olugbenga S Michael, Olufunke O Falayi, Praghalathan Kanthakumar, Pratheesh D Mankuzhy, Hitesh Soni, Adebowale Adebiyi

Erratum issuedOpen access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microvascular research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Pacemaking in the lymphatic system.The Journal of physiology · 2026
    Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jeremiah M AfolabiDepartment of Physiology, College of Medicine, University of Tennessee Health Science Center, Memphis, TN, USA.
Olugbenga S MichaelDepartment of Physiology, College of Medicine, University of Tennessee Health Science Center, Memphis, TN, USA.
Olufunke O FalayiDepartment of Physiology, College of Medicine, University of Tennessee Health Science Center, Memphis, TN, USA.
Praghalathan KanthakumarDepartment of Physiology, College of Medicine, University of Tennessee Health Science Center, Memphis, TN, USA.
Pratheesh D MankuzhyDepartment of Physiology, College of Medicine, University of Tennessee Health Science Center, Memphis, TN, USA.
Hitesh SoniDepartment of Physiology, College of Medicine, University of Tennessee Health Science Center, Memphis, TN, USA.
Adebowale AdebiyiDepartment of Physiology, College of Medicine, University of Tennessee Health Science Center, Memphis, TN, USA. Electronic address: aadebiyi@uthsc.edu.
University of Tennessee Health Science Center · US

Funding

Urotensin II and renal insufficiency in growth-restricted infants.R01DK127625 · NIDDK · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI ADEBIYI, ADEBOWALE · 2020 to 2024
$3.0M
Vascular ion channels and microcirculation in neonatal urinary tract obstructionR01DK120595 · NIDDK · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI ADEBIYI, ADEBOWALE · 2020 to 2024
$2.7M
NIDDK NIH HHS R01 DK120595NIDDK NIH HHS R01 DK127625
6 · The paper itself

Abstract

Control of microvascular reactivity by 5-hydroxytryptamine (5-HT; serotonin) is complex and may depend on vascular bed type and 5-HT receptors. 5-HT receptors consist of seven families (5-HT

Indexed as

Muscle, Smooth, VascularSerotoninAnimalsCHO CellsCricetinaeCricetulusHumansInfant, NewbornKidneyReceptors, SerotoninSwineTRPV Cation ChannelsReceptors, SerotoninSerotoninTRPV4 protein, humanTRPV Cation Channels5-HTNeonatal kidney functionRenal vasoregulationTRPV4

Identifiers

PMID36889668
PMCPMC10258165
OpenAlexW4323322249

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.