ArticleRadiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology2023
Recurrence analysis of glioblastoma cases based on distance and dose information.
Article in Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Multidisciplinary treatment is necessary in glioblastoma with extracerebral metastases.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2025Pooled it
- Recurrence distance analysis for clinical target volume optimization in glioblastoma.Clinical and translational radiation oncology · 2026Article
- Impact on survival of glioblastoma patients in relation to the imaging of the peri-surgical area: a multi-parametric diffusion MRI, perfusion MRI, and [11C]MET PET study.The British journal of radiology · 2026Article
- Supramaximal resection in gliomas: a narrative review of surgical techniques, clinical outcomes, and ethical considerations.Annals of medicine and surgery (2012) · 2026Review
- Comparative analysis of outcome, recurrence patterns, and dosimetry in glioblastoma patients treated according to RTOG versus EORTC contouring guidelines.Neuro-oncology practice · 2026Article
- Limitations of Gliadel Wafers and Strategies for Next-Generation Local Delivery Systems for Glioblastoma.Cancers · 2026Review
- Does pattern of 5-aminolevulinic acid (5-ALA) residual intra-operatively predict worse outcome in glioblastoma?Brain & spine · 2026Article
- Case Report: Endoscopic dual-port surgery via the previous resection cavity for recurrent glioblastoma.Frontiers in surgery · 2026Article
- Spinal Metastasis from Supratentorial Glioblastoma: A Registry-Based Case Series and a Review of the Literature.Cancers · 2025Article
- A white matter-centered approach to investigate recurrence pathways in high-grade gliomas: a single-center retrospective study.Journal of neuro-oncology · 2025Article
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- Recurrence pattern of glioblastoma treated with intensity-modulated radiation therapy versus three-dimensional conformal radiation therapy.Radiation oncology journal · 2024Article
- Comparison of different target volume delineation strategies based on recurrence patterns in adjuvant radiotherapy for glioblastoma.Neuro-oncology practice · 2024Article
- Dosimetric feasibility analysis and presentation of an isotoxic dose-escalated radiation therapy concept for glioblastoma used in the PRIDE trial (NOA-28; ARO-2022-12).Clinical and translational radiation oncology · 2024Article
- The influence of anisotropy on the clinical target volume of brain tumor patients.Physics in medicine and biology · 2024Article
- A multicenter analysis of prognostic factors for patients undergoing re-irradiation for recurrent glioblastoma.Neuro-oncology advancesArticle
Corrections and comments
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7 authors.
Funding
Abstract
background and purposeRadiation therapy for glioblastoma (GBM) typically involves large target volumes. The aim of this study was to examine the recurrence pattern of GBM following modern radiochemotherapy according to EORTC guidelines and provide dose and distance information for the choice of optimal target volume margins. MATERIALS AND
methodsIn this study, the recurrences of 97 GBM patients, treated with radiochemotherapy from 2013 to 2017 at the Medical Center- University of Freiburg, Germany were analysed. Dose and distance based metrices were used to derive recurrence patterns.
resultsThe majority of recurrences (75%) occurred locally within the primary tumor area. Smaller GTVs had a higher rate of distant recurrences. Larger treated volumes did not show a clinical benefit regarding progression free and overall survival.
conclusionThe identified recurrence pattern suggests that adjustments or reductions in target volume margins are feasible and could result in similar survival rates, potentially combined with a lower risk of side effects.
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